Membrane cartridges for endotoxin removal from interferon preparations
文献类型：期刊论文
| 作者 | Li, JH; Shao, YG; Chen, ZA; Cong, RZ; Wang, JD; Liu, XL |
| 刊名 | journal of chromatography b-analytical technologies in the biomedical and life sciences
 |
| 出版日期 | 2003-07-05 |
| 卷号 | 791期号:1-2页码:55-61 |
| 关键词 | membrane cartridges cellulose membrane interferon chitosan deoxycholate endotoxin |
| 产权排序 | 1;1 |
| 英文摘要 | the suitability of membrane cartridges for the removal of endotoxin from both distilled water and interferon preparations was examined. the endotoxin concentrations were reduced to 4.0 and 7.3 eu/ml, respectively, when about 4000 ml of distilled water with 20 and 28 eu/ml were passed through the deoxycholate and chitosan immobilized membrane cartridges. when 200 ml of interferon preparation with endotoxin concentration more than 80 eu/ml and ph 3.9 were applied to a deoxycholate immobilized membrane cartridge at a flow-rate of 9 ml/min, the endotoxin concentration was reduced to less than 10 eu/ml. however, if an interferon preparation of 450 ml, with more than 80 eu/ml of endotoxin and ph 3.9 was applied to the chitosan immobilized membrane cartridge at a flow-rate of 18 ml/min, the endotoxin concentration was reduced to less than 10 eu/ml. (c) 2003 elsevier science b.v. all rights reserved. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
| 类目[WOS] | biochemical research methods ; chemistry, analytical |
| 研究领域[WOS] | biochemistry & molecular biology ; chemistry |
| 关键词[WOS] | affinity sorbents ; adsorbers |
| 收录类别 | SCI |
| 原文出处 | true |
| 语种 | 英语 |
| WOS记录号 | WOS:000183646000007 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/82725]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116012, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, JH,Shao, YG,Chen, ZA,et al. Membrane cartridges for endotoxin removal from interferon preparations[J]. journal of chromatography b-analytical technologies in the biomedical and life sciences,2003,791(1-2):55-61. |
| APA | Li, JH,Shao, YG,Chen, ZA,Cong, RZ,Wang, JD,&Liu, XL.(2003).Membrane cartridges for endotoxin removal from interferon preparations.journal of chromatography b-analytical technologies in the biomedical and life sciences,791(1-2),55-61. |
| MLA | Li, JH,et al."Membrane cartridges for endotoxin removal from interferon preparations".journal of chromatography b-analytical technologies in the biomedical and life sciences 791.1-2(2003):55-61. |
入库方式： OAI收割
来源：大连化学物理研究所
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