The study on a PVC membrane electrode for gemfibrozil
文献类型：期刊论文
| 作者 | Xu, F; Sun, LX; Matsuda, N; Okada, T; Tan, ZC; Liang, JG |
| 刊名 | biological & pharmaceutical bulletin
 |
| 出版日期 | 2002-02-01 |
| 卷号 | 25期号:2页码:165-167 |
| 关键词 | gemfibrozil ion selective electrode orthogonal experimental design quantitative determination |
| 英文摘要 | in this paper, a poly(vinyl chloride) (pvc) membrane electrode is prepared for gemfibrozil, 2, 2-dimethyl-5(2,5-xylyloxy) valeric acid, based on its ion pair complexes with hexadecyltrioctyl ammonium iodide (htoa). the membrane composition of the electrode was optimized by using the sequential level elimination method for orthogonal experimental design. the electrode has a nernstian response range from 2.5 x 10(-5) to 0.1 mol/l with an average slope of 55.3 mv/decade. the limit of detection is 7.1 x 10(-6) mol/l. the electrode responses were not affected by ph in the range 10.0-12.3. a na2b4o7-na2co3 buffer of ph = 11.0 was selected as the background electrolyte solution for potentiometric measurements. the electrode was used for determining gemfibrozil in pharmaceutical preparations with satisfactory results. |
| WOS标题词 | science & technology ; life sciences & biomedicine |
| 类目[WOS] | pharmacology & pharmacy |
| 研究领域[WOS] | pharmacology & pharmacy |
| 关键词[WOS] | chromatographic determination ; plasma ; metabolites ; urine |
| 收录类别 | SCI |
| 原文出处 | true |
| 语种 | 英语 |
| WOS记录号 | WOS:000173615100002 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/83165]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.Jinan Univ, Dept Chem, Guangzhou 510632, Peoples R China 3.Natl Inst Adv Ind Sci & Technol, Nanoarchitecton Res Ctr, Tsukuba, Ibaraki 3058565, Japan 4.Natl Inst Adv Ind Sci & Technol, Electrochem Energy Conver Lab, Tsukuba, Ibaraki 3058565, Japan 5.Human Inst Drug Detect, Changsha 410001, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, F,Sun, LX,Matsuda, N,et al. The study on a PVC membrane electrode for gemfibrozil[J]. biological & pharmaceutical bulletin,2002,25(2):165-167. |
| APA | Xu, F,Sun, LX,Matsuda, N,Okada, T,Tan, ZC,&Liang, JG.(2002).The study on a PVC membrane electrode for gemfibrozil.biological & pharmaceutical bulletin,25(2),165-167. |
| MLA | Xu, F,et al."The study on a PVC membrane electrode for gemfibrozil".biological & pharmaceutical bulletin 25.2(2002):165-167. |
入库方式： OAI收割
来源：大连化学物理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。