Application of probabilistic neural network in the clinical diagnosis of cancers based on clinical chemistry data
文献类型：期刊论文
| 作者 | Shan, YC; Zhao, RH; Xu, GW; Liebich, HM; Zhang, YK |
| 刊名 | analytica chimica acta
 |
| 出版日期 | 2002-10-23 |
| 卷号 | 471期号:1页码:77-86 |
| 关键词 | classification cancer nucleosides probabilistic neural network |
| 英文摘要 | as a recently developed and powerful classification tool, probabilistic neural network was used to distinguish cancer patients from healthy persons according to the levels of nucleosides in human urine. two datasets (containing 32 and 50 patterns, respectively) were investigated and the total consistency rate obtained was 100% for dataset 1 and 94% for dataset 2. to evaluate the performance of probabilistic neural network, linear discriminant analysis and learning vector quantization network, were also applied to the classification problem. the results showed that the predictive ability of the probabilistic neural network is stronger than the others in this study. moreover, the recognition rate for dataset 2 can achieve to 100% if combining, these three methods together, which indicated the promising potential of clinical diagnosis by combining different methods. (c) 2002 elsevier science b.v. all rights reserved. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, analytical |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | mass-spectrometry ; modified nucleosides ; pattern-recognition ; retention behavior ; sensor array ; identification ; classification ; chromatography ; classifiers ; tool |
| 收录类别 | SCI |
| 原文出处 | true |
| 语种 | 英语 |
| WOS记录号 | WOS:000178565700008 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/83249]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Acad Sinica, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116011, Peoples R China 2.Univ Tubingen, Med Klin, D-72076 Tubingen, Germany |
| 推荐引用方式 GB/T 7714 | Shan, YC,Zhao, RH,Xu, GW,et al. Application of probabilistic neural network in the clinical diagnosis of cancers based on clinical chemistry data[J]. analytica chimica acta,2002,471(1):77-86. |
| APA | Shan, YC,Zhao, RH,Xu, GW,Liebich, HM,&Zhang, YK.(2002).Application of probabilistic neural network in the clinical diagnosis of cancers based on clinical chemistry data.analytica chimica acta,471(1),77-86. |
| MLA | Shan, YC,et al."Application of probabilistic neural network in the clinical diagnosis of cancers based on clinical chemistry data".analytica chimica acta 471.1(2002):77-86. |
入库方式： OAI收割
来源：大连化学物理研究所
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