Preparation of uniform calcium alginate gel beads by membrane emulsification coupled with internal gelation
文献类型：期刊论文
| 作者 | Liu, XD; Bao, DC; Xue, WM; Xiong, Y; Yu, WT; Yu, XJ; Ma, XJ; Yuan, Q |
| 刊名 | journal of applied polymer science
 |
| 出版日期 | 2003-01-31 |
| 卷号 | 87期号:5页码:848-852 |
| 关键词 | polyelectrolytes gels drug delivery systems membranes gelation |
| 产权排序 | 1;1 |
| 英文摘要 | with the objective of making calcium alginate gel beads with small and uniform size, membrane emulsification coupled with internal gelation was proposed. spherical gel beads with mean size of about 50 mum, and even smaller ones in water, and with narrow size distribution were successfully obtained. experimental studies focusing mainly on the effect of process parameters on bead properties were performed. the size of the beads was mainly dependent on the diameter of the membrane pores. high transmembrane pressure made for large gel beads with wide size distribution. low sodium alginate concentration produced nonspherical beads, whereas a high concentration was unsuitable for the production of small beads with narrow distribution. thus 1.5% w/v was enough. a high surfactant concentration favored the formation of small beads, but the adverse effect on mass transfer should be considered in this novel process. (c) 2002 wiley periodicals, inc. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | polymer science |
| 研究领域[WOS] | polymer science |
| 关键词[WOS] | albumin microspheres ; particle-size ; delivery ; microparticles |
| 收录类别 | SCI |
| 原文出处 | true |
| 语种 | 英语 |
| WOS记录号 | WOS:000179735700016 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/83375]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Lab Biomed Mat Engn, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, XD,Bao, DC,Xue, WM,et al. Preparation of uniform calcium alginate gel beads by membrane emulsification coupled with internal gelation[J]. journal of applied polymer science,2003,87(5):848-852. |
| APA | Liu, XD.,Bao, DC.,Xue, WM.,Xiong, Y.,Yu, WT.,...&Yuan, Q.(2003).Preparation of uniform calcium alginate gel beads by membrane emulsification coupled with internal gelation.journal of applied polymer science,87(5),848-852. |
| MLA | Liu, XD,et al."Preparation of uniform calcium alginate gel beads by membrane emulsification coupled with internal gelation".journal of applied polymer science 87.5(2003):848-852. |
入库方式： OAI收割
来源：大连化学物理研究所
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