Multivariate optimization in micellar electrokinetic capillary chromatography
文献类型：期刊论文
| 作者 | Lee, RJ; Liu, Z; Zou, HF; Ni, JY; Zhang, YK |
| 刊名 | journal of microcolumn separations
 |
| 出版日期 | 2000-06-01 |
| 卷号 | 12期号:6页码:356-365 |
| 关键词 | uniform design iterative optimization aromatic compounds MECC organic modifiers |
| 英文摘要 | the optimization of the organic modifier concentration in micellar electrokinetic capillary chromatography (mecc) has been achieved by a uniform design and iterative optimization method, which has been developed for the optimization of composition of the mobile phase in high performance liquid chromatography. according to the proposed method, the uniform design technique has been applied to design the starting experiments, which can reduce the number of experiments compared with traditional simultaneous methods, such as the orthano design. the hierarchical chromatographic response function has been modified to evaluate the separation quality of a chromatogram in mecc. an iterative procedure has been adopted to search the optimal concentration of organic modifiers for improving the accuracy of retention predicted and the quality of the chromatogram. validity of the optimization method has been proved by the separation of 31 aromatic compounds in mecc. (c) 2000 john wiley & sons, inc. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, analytical |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | resolution mapping scheme ; organic modifiers ; mobile phase ; separation ; selectivity ; sulfonamides ; urea |
| 收录类别 | SCI |
| 原文出处 | true |
| 语种 | 英语 |
| WOS记录号 | WOS:000087951900004 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/84041]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116011, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lee, RJ,Liu, Z,Zou, HF,et al. Multivariate optimization in micellar electrokinetic capillary chromatography[J]. journal of microcolumn separations,2000,12(6):356-365. |
| APA | Lee, RJ,Liu, Z,Zou, HF,Ni, JY,&Zhang, YK.(2000).Multivariate optimization in micellar electrokinetic capillary chromatography.journal of microcolumn separations,12(6),356-365. |
| MLA | Lee, RJ,et al."Multivariate optimization in micellar electrokinetic capillary chromatography".journal of microcolumn separations 12.6(2000):356-365. |
入库方式： OAI收割
来源：大连化学物理研究所
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