Efficient synthesis of α-alkylidene-β-lactams via NaOH-promoted intramolecular aza-Michael addition of α-carbamoyl ketene-S,S-acetals in aqueous media
文献类型：期刊论文
| 作者 | Yang Y ; Xiang DX ; Zhao XL ; Liang YJ ; Huang J ; Dong DW |
| 刊名 | Tetrahedron
 |
| 出版日期 | 2008 |
| 卷号 | 64期号:22页码:4959-4966 |
| 关键词 | aqueous media 2-azetidinone beta-lactams Michael addition vilsmeier reagent |
| ISSN号 | 0040-4020 |
| 通讯作者 | Dewen Dong |
| 中文摘要 | A facile and efficient synthesis of substituted alpha-alkylidene-beta-lactams have been developed via a NaOH-promoted intramolecular aza-Michael addition of alpha-carbamoyl, alpha-(1-chlorovinyl) ketene-S,S-acetals and subsequent nucleophilic vinylic substitution (SNV) reaction in alcoholic aqueous media. (C) 2008 Elsevier Ltd. All rights reserved. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2010-04-14 ; 2011-06-09 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/9709]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Yang Y,Xiang DX,Zhao XL,et al. Efficient synthesis of α-alkylidene-β-lactams via NaOH-promoted intramolecular aza-Michael addition of α-carbamoyl ketene-S,S-acetals in aqueous media[J]. Tetrahedron,2008,64(22):4959-4966. |
| APA | Yang Y,Xiang DX,Zhao XL,Liang YJ,Huang J,&Dong DW.(2008).Efficient synthesis of α-alkylidene-β-lactams via NaOH-promoted intramolecular aza-Michael addition of α-carbamoyl ketene-S,S-acetals in aqueous media.Tetrahedron,64(22),4959-4966. |
| MLA | Yang Y,et al."Efficient synthesis of α-alkylidene-β-lactams via NaOH-promoted intramolecular aza-Michael addition of α-carbamoyl ketene-S,S-acetals in aqueous media".Tetrahedron 64.22(2008):4959-4966. |
入库方式： OAI收割
来源：长春应用化学研究所
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