On the chemical synthesis and drug delivery response of folate receptor-activated, polyethylene glycol-functionalized magnetite nanoparticles
文献类型：期刊论文
| 作者 | Zhang J ; Rana S ; Srivastava RS ; Misra RDK |
| 刊名 | acta biomaterialia
 |
| 出版日期 | 2008 |
| 卷号 | 4期号:1页码:40－48 |
| 关键词 | IRON-OXIDE NANOPARTICLES SUPERPARAMAGNETIC NANOPARTICLES BIOMEDICAL APPLICATIONS PHOTODYNAMIC THERAPY TARGETED DELIVERY RELEASE KINETICS CELLULAR UPTAKE GENE-THERAPY CARRIER SYSTEM |
| ISSN号 | 1742-7061 |
| 通讯作者 | misra rdk |
| 中文摘要 | we describe here the chemical synthesis and in vitro drug delivery response of polyethylene glycol (peg)-functionalized magnetite (fe3o4) nanoparticles, which were activated with a stable ligand, folic acid, and conjugated with an anticancer drug, doxorubicin. the functionalization and conjugation steps in the chemical synthesis were confirmed using fourier transform infrared spectroscopy. the drug-release behavior of peg-functionalized and folic acid-doxorubicin-conjugated magnetic nanoparticles was characterized by two stages involving an initial rapid release, followed by a controlled release. (c) 2007 acta materialia inc. published by elsevier ltd. all rights reserved. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2010-04-14 ; 2011-06-09 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/9831]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Zhang J,Rana S,Srivastava RS,et al. On the chemical synthesis and drug delivery response of folate receptor-activated, polyethylene glycol-functionalized magnetite nanoparticles[J]. acta biomaterialia,2008,4(1):40－48. |
| APA | Zhang J,Rana S,Srivastava RS,&Misra RDK.(2008).On the chemical synthesis and drug delivery response of folate receptor-activated, polyethylene glycol-functionalized magnetite nanoparticles.acta biomaterialia,4(1),40－48. |
| MLA | Zhang J,et al."On the chemical synthesis and drug delivery response of folate receptor-activated, polyethylene glycol-functionalized magnetite nanoparticles".acta biomaterialia 4.1(2008):40－48. |
入库方式： OAI收割
来源：长春应用化学研究所
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