中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Layer-by-layer assembly of biologically inert inorganic ions/DNA multilayer films for tunable DNA release by chelation

文献类型:期刊论文

作者Wang F ; Wang JL ; Zhai YM ; Li GP ; Li D ; Dong SJ
刊名journal of controlled release    
出版日期2008
卷号132期号:1页码:65–73
关键词SURFACE-PLASMON RESONANCE POLYELECTROLYTE MULTILAYERS GENE DELIVERY COMPLEXES ELECTROCHEMISTRY CONSTRUCTION POLYPEPTIDE MOLECULES ZIRCONIUM COATINGS
ISSN号0168-3659
通讯作者dong sj
中文摘要in this work, we illustrate a simple chelation-based strategy to trigger dna release from dna-incorporated multilayer films, which were fabricated through the layer-by-layer (lbl) assembly of dna and inorganic zirconium (iv) ion (zr4+). after being incubated in several kinds of chelator solutions, the dna multilayer films disassembled and released the incorporated dna. this was most probably due to the cleavage of coordination/electrostatic interactions between zr4+ and phosphate groups of dna. surface plasmon resonance (spr), uv-vis spectrometry and atomic force microscopy (afm) were used to characterize the assembly and the disassembly of the films.
收录类别SCI
语种英语
WOS记录号WOS:000261354400010
公开日期2010-04-14
源URL[http://ir.ciac.jl.cn/handle/322003/9943]  
专题长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式
GB/T 7714
Wang F,Wang JL,Zhai YM,et al. Layer-by-layer assembly of biologically inert inorganic ions/DNA multilayer films for tunable DNA release by chelation[J]. journal of controlled release    ,2008,132(1):65–73.
APA Wang F,Wang JL,Zhai YM,Li GP,Li D,&Dong SJ.(2008).Layer-by-layer assembly of biologically inert inorganic ions/DNA multilayer films for tunable DNA release by chelation.journal of controlled release    ,132(1),65–73.
MLA Wang F,et al."Layer-by-layer assembly of biologically inert inorganic ions/DNA multilayer films for tunable DNA release by chelation".journal of controlled release     132.1(2008):65–73.

入库方式: OAI收割

来源:长春应用化学研究所

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