Application of supported phospholipids bilayer bilayers for biosensor based on imaging ellipsometry
文献类型:会议论文
作者 | Chen YY; Zhang YB; Wang CX![]() ![]() ![]() |
出版日期 | 2009 |
会议名称 | World Congress on Medical Physics and Biomedical Engineering: Micro- and Nanosystems in Medicine, Active Implants, Biosensors |
会议日期 | September 7, 2009 - September 12, 2009 |
会议地点 | Munich, Germany |
关键词 | Bi-layer Carboxyl groups Covalent immobilization Functionalized Imaging ellipsometry Microfiuidic array Non-specific protein adsorption Phospholipids bilayer Silicon surfaces Supported phospholipid bilayers |
通讯作者 | Chang, W. R. (wrchang@sun5.ibp.ac.cn) |
中文摘要 | Application of supported phospholipids bilayers (SPB) is presented for biosensor based on imaging ellipsometry. One SPB is prepared by covalent immobilization of phospholipids monolayer on silicon surface, and followed by adsorption of PEG functionalized phospholipids layer. Another is prepared by adsorption of the mixture of phospholipids and PEG functionalized phospholipids on the hydrophilic silicon surface. Results show that obvious resistance to non-specific protein adsorption on SPB is obtained, and proteins covalently immobilized on the bilayers by the terminal carboxyl group of PEG remain higher bioactivity than that immobilized on silicon surface directly. © 2009 Springer-Verlag. |
收录类别 | EI |
会议网址 | 10.1007/978-3-642-03887-7_45 |
会议录 | IFMBE Proceedings
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语种 | 英语 |
ISBN号 | 9783642038860 |
源URL | [http://dspace.imech.ac.cn/handle/311007/60454] ![]() |
专题 | 力学研究所_国家微重力实验室 |
推荐引用方式 GB/T 7714 | Chen YY,Zhang YB,Wang CX,et al. Application of supported phospholipids bilayer bilayers for biosensor based on imaging ellipsometry[C]. 见:World Congress on Medical Physics and Biomedical Engineering: Micro- and Nanosystems in Medicine, Active Implants, Biosensors. Munich, Germany. September 7, 2009 - September 12, 2009.10.1007/978-3-642-03887-7_45. |
入库方式: OAI收割
来源:力学研究所
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