Assembled dendritic titanium catalysts for enantioselective hetero-Diels-Alder reaction of aldehydes with danishefsky's diene
文献类型：期刊论文
| 作者 | Ji BM(吉保明) ; Yuan Y(袁宇) ; Ding KL(丁奎岭) ; Meng JB(孟继本) |
| 刊名 | Chem.-Eur. J.
 |
| 出版日期 | 2003 |
| 卷号 | 9期号:24页码:5989-5996 |
| ISSN号 | 0947-6539 |
| 其他题名 | 组装的树枝状钛催化剂用于不对称杂D-A反应 |
| 通讯作者 | 丁奎岭 |
| 英文摘要 | A new type of dendritic 2-amino-2'-hydroxy-1,1'-binaphthyl (NOBIN)-derived schiff-base ligands have been synthesized and applied to the tianium-catalyzed heter-Diels-Alder reaction f Danishefsky's diene with aldehydes. These reactions afforded the corresponding 2-substituted 2,3-dihydro-4H-pyran-4-ones in quantitative yields and with excellent enantioselectivities (up to 97.2% ee.). The disposition of the dendritic wedges and the dendron size in the ligands were found to have significant impact on the enantioselectivity of the reaction. The recovered dendritic catalyst could be reused without further addition of the Ti source or a carboxylic acid additive for at least three cycles, retaining simi- lar activity and enantioselectivity. The high stability of this type of assembled dendritic titanium catalyst may be at- tributed to the stabilization effect of large-sized dendron units in the cata- lyst molecule. The other important phenomenon observed with this cata-lyst system is that a higher degree of asymmetric amplification has been ach-ieved by attachment of the dendron unit to the chiral ligand, which repre-sents a new advantage of dendrimer catalysts for asymmetric reactions using chiral ligands of lower optical purity. |
| 学科主题 | 金属有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1002/chem.200305141 |
| 语种 | 英语 |
| WOS记录号 | WOS:000187425200004 |
| 公开日期 | 2013-02-22 |
| 源URL | [http://202.127.28.38/handle/331003/17765]  |
| 专题 | 上海有机化学研究所_金属有机化学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Ji BM,Yuan Y,Ding KL,et al. Assembled dendritic titanium catalysts for enantioselective hetero-Diels-Alder reaction of aldehydes with danishefsky's diene[J]. Chem.-Eur. J.,2003,9(24):5989-5996. |
| APA | 吉保明,袁宇,丁奎岭,&孟继本.(2003).Assembled dendritic titanium catalysts for enantioselective hetero-Diels-Alder reaction of aldehydes with danishefsky's diene.Chem.-Eur. J.,9(24),5989-5996. |
| MLA | 吉保明,et al."Assembled dendritic titanium catalysts for enantioselective hetero-Diels-Alder reaction of aldehydes with danishefsky's diene".Chem.-Eur. J. 9.24(2003):5989-5996. |
入库方式： OAI收割
来源：上海有机化学研究所
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