中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Coating Didodecyldimethylammonium Bromide onto Au Nanoparticles Increases the Stability of Its Complex with DNA

文献类型:期刊论文

作者Li PC ; Zhang LX ; Ai KL ; Li D ; Liu XH ; Wang EK
刊名journal of controlled release
出版日期2008
卷号129期号:2页码:128-134
关键词NONVIRAL GENE DELIVERY GOLD NANOPARTICLES CATIONIC LIPOSOMES CELL TRANSFECTION MAMMALIAN-CELLS IN-VITRO ANTISENSE OLIGONUCLEOTIDES COLUMNAR PHASE PLASMID DNA THERAPY
ISSN号0168-3659
通讯作者wang ek
中文摘要the stability of the complex of cationic lipid with nucleic acid, especially when facing serum, is crucial for the efficiency of gene delivery. here, we demonstrated that the stability of the complex of didodecyldimethylammonium bromide (ddab, a cationic lipid) with dna in the presence of serum dramatically increased after coating ddab onto the surface of the gold nanoparticles. the stability of the complex was demonstrated with dye intercalation assay, and agarose gel electrophoresis.
收录类别SCI
语种英语
WOS记录号WOS:000257959400010
公开日期2010-04-14
源URL[http://ir.ciac.jl.cn/handle/322003/10385]  
专题长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式
GB/T 7714
Li PC,Zhang LX,Ai KL,et al. Coating Didodecyldimethylammonium Bromide onto Au Nanoparticles Increases the Stability of Its Complex with DNA[J]. journal of controlled release,2008,129(2):128-134.
APA Li PC,Zhang LX,Ai KL,Li D,Liu XH,&Wang EK.(2008).Coating Didodecyldimethylammonium Bromide onto Au Nanoparticles Increases the Stability of Its Complex with DNA.journal of controlled release,129(2),128-134.
MLA Li PC,et al."Coating Didodecyldimethylammonium Bromide onto Au Nanoparticles Increases the Stability of Its Complex with DNA".journal of controlled release 129.2(2008):128-134.

入库方式: OAI收割

来源:长春应用化学研究所

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