DNAzyme-based Colorimetric Sensing of Lead (Pb2+) Using Unmodified Gold Nanoparticle Probes
文献类型：期刊论文
| 作者 | Wei H ; Li BL ; Li J ; Dong SJ ; Wang EK |
| 刊名 | nanotechnology
 |
| 出版日期 | 2008 |
| 卷号 | 19期号:9页码:文献编号：095501 |
| 关键词 | RNA-CLEAVING DEOXYRIBOZYME IN-VITRO SELECTION SINGLE-STRANDED-DNA CATALYTIC DNA ELECTROCHEMICAL DETECTION APTAMER ENZYMES BIOSENSOR THROMBIN SPECTROMETRY |
| ISSN号 | 0957-4484 |
| 通讯作者 | wei h |
| 中文摘要 | novel functional oligonucleotides, especially dnazymes with rna-cleavage activity, have been intensively studied due to their potential applications in therapeutics and sensors. taking advantage of the high specificity of 17e dnazyme for pb2+, highly sensitive and selective fluorescent, electrochemical and colorimetric sensors have been developed for pb2+. in this work, we report a simple, sensitive and label-free 17e dnazyme-based sensor for pb2+ detection using unmodified gold nanoparticles (gnps) based on the fact that unfolded single-stranded dna could be adsorbed on the citrate protected gnps while double-stranded dna could not. by our method the substrate cleavage by the 17e dnazyme in the presence of pb2+ could be monitored by color change of gnps, thereby pb2+ detection was realized. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2010-04-14 ; 2011-06-09 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/10399]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Wei H,Li BL,Li J,et al. DNAzyme-based Colorimetric Sensing of Lead (Pb2+) Using Unmodified Gold Nanoparticle Probes[J]. nanotechnology,2008,19(9):文献编号：095501. |
| APA | Wei H,Li BL,Li J,Dong SJ,&Wang EK.(2008).DNAzyme-based Colorimetric Sensing of Lead (Pb2+) Using Unmodified Gold Nanoparticle Probes.nanotechnology,19(9),文献编号：095501. |
| MLA | Wei H,et al."DNAzyme-based Colorimetric Sensing of Lead (Pb2+) Using Unmodified Gold Nanoparticle Probes".nanotechnology 19.9(2008):文献编号：095501. |
入库方式： OAI收割
来源：长春应用化学研究所
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