The X-ray structures of HOBt-based immonium-type coupnng reagents and the rearrangement of benzotriazolyl esters of Na-protected amino acids or peptides:N-vs. O-substituted forms
文献类型：期刊论文
| 作者 | Li P(李鹏) ; Xu JC(徐杰诚) |
| 刊名 | J. Chem. Soc.-Perkin Trans. 2
 |
| 出版日期 | 2001 |
| 期号 | 1页码:113-120 |
| ISSN号 | 1472-779X |
| 其他题名 | HOBt亚胺型缩合剂及其N－保护氨基或肽酯的重排物的X衍射结构 |
| 通讯作者 | 徐杰诚 |
| 英文摘要 | The crystal structures of HOBt-based immonium salts BOMI and BDMP are reported and show that these compounds crystallze as the N-substituted form rather than as the previously assigned O-substituted form. These unexpected phenomena are explained well bysemiempirical PM3 calculations; the crystal structures of other HOBt-based onium salts can also be predicted by these theoretical calculations. The reaction mechanisms for coupling reactions mediated by these HOBt-based immonium salts and the rearrangement of the benzotriazolyl ester intermediate generated during the coupling reactions were studied by both experimental observations and theoretical calculations. The crystal structures of these benzotriazolyl esters were predicted by PM3 calculations and verified by reported X-ray data. |
| 学科主题 | 生命有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1039/b003930f |
| 语种 | 英语 |
| 公开日期 | 2013-03-04 |
| 源URL | [http://202.127.28.38/handle/331003/22642]  |
| 专题 | 上海有机化学研究所_上海有机化学研究所 |
| 推荐引用方式 GB/T 7714 | Li P,Xu JC. The X-ray structures of HOBt-based immonium-type coupnng reagents and the rearrangement of benzotriazolyl esters of Na-protected amino acids or peptides:N-vs. O-substituted forms[J]. J. Chem. Soc.-Perkin Trans. 2,2001(1):113-120. |
| APA | 李鹏,&徐杰诚.(2001).The X-ray structures of HOBt-based immonium-type coupnng reagents and the rearrangement of benzotriazolyl esters of Na-protected amino acids or peptides:N-vs. O-substituted forms.J. Chem. Soc.-Perkin Trans. 2(1),113-120. |
| MLA | 李鹏,et al."The X-ray structures of HOBt-based immonium-type coupnng reagents and the rearrangement of benzotriazolyl esters of Na-protected amino acids or peptides:N-vs. O-substituted forms".J. Chem. Soc.-Perkin Trans. 2 .1(2001):113-120. |
入库方式： OAI收割
来源：上海有机化学研究所
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