IN THE PURSUIT OF A BETTER SWEETENER
文献类型：期刊论文
| 作者 | Ceng GZ(曾广植) ; Chen JT(陈金泰) ; He HZ(何华中) ; Wang ZQ(王肇卿) ; Yan JS(严家生) |
| 刊名 | J. Agric. Food Chem.
 |
| 出版日期 | 1991 |
| 卷号 | 39期号:4页码:782-785 |
| ISSN号 | 0021-8561 |
| 其他题名 | IN THE PURSUIT OF A BETTER SWEETENER |
| 通讯作者 | 曾广植 |
| 英文摘要 | Dipeptide sweeteners of the AspNHCH(R1)COR type, where R1 = H, Me, CH2OH, and CO2Me and R = OR2 or NHR2 with R2 less-than-or-equal-to C10 atoms, i.e., alkyl, aryl, heterocyclic, bi- or tricyclic group, were synthesized to remedy the well-known shortcomings of aspartame. For the design of these sweeteners, the classic theory of Cohn-Oertly-Myers, Ariyoshi's rule of steric size difference, Newman's rule of H-6 number as well as our C-9 rule and a model of induced fitting of multiple-point attachment with the sweet receptor were employed. On the basis of our results as well as those of others, qualitative and semi-quantitative structure-activity relationships were discussed according to the current concepts of polar-steric-hydrophobic factor analyses for the pursuit of an ideal high sweetness potency dipeptide sweetener. Compounds of high sweetness potency prepared in this work are all of high stabilities and indifferent to microorganisms or any known genetic diseases. |
| 学科主题 | 有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1021/jf00004a033 |
| 语种 | 英语 |
| 公开日期 | 2013-03-11 |
| 源URL | [http://202.127.28.38/handle/331003/23994]  |
| 专题 | 上海有机化学研究所_上海有机化学研究所 |
| 推荐引用方式 GB/T 7714 | Ceng GZ,Chen JT,He HZ,et al. IN THE PURSUIT OF A BETTER SWEETENER[J]. J. Agric. Food Chem.,1991,39(4):782-785. |
| APA | 曾广植,陈金泰,何华中,王肇卿,&严家生.(1991).IN THE PURSUIT OF A BETTER SWEETENER.J. Agric. Food Chem.,39(4),782-785. |
| MLA | 曾广植,et al."IN THE PURSUIT OF A BETTER SWEETENER".J. Agric. Food Chem. 39.4(1991):782-785. |
入库方式： OAI收割
来源：上海有机化学研究所
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