Tetrahydroisoquinoline based sulfonamide hydroxamates as potent matrix metalloproteinase inhibitors
文献类型：期刊论文
| 作者 | Ma DW(马大为) ; Wu WG(吴问根) ; Yang GX(杨国新) ; LI JINGYA ; Li J(李佳) ; Ye QZ(叶其壮) |
| 刊名 | Bioorg. Med. Chem. Lett.
 |
| 出版日期 | 2004 |
| 卷号 | 14期号:1页码:47-50 |
| ISSN号 | 0960-894X |
| 其他题名 | Tetrahydroisoquinoline based sulfonamide hydroxamates as potent matrix metalloproteinase inhibitors |
| 通讯作者 | 马大为 ; 叶其壮 |
| 英文摘要 | The synthesis and MMP inhibitory activity of a series of tetrahydroisoquinoline based sulfonamide hydroxamates are described. In nine MMPs tested, most of the compounds display potent inhibition activity except for MMP-7. Some subtle isozyme selectivity is observed by varying the substituents at the 6- and 7-positions and aromatic ring of arylsulfonyl groups. (C) 2003 Elsevier Ltd. All rights reserved. |
| 学科主题 | 生命有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1016/j.bmcl.2003.10.026 |
| 语种 | 英语 |
| WOS记录号 | WOS:000187862000007 |
| 公开日期 | 2013-02-19 |
| 源URL | [http://202.127.28.38/handle/331003/15473]  |
| 专题 | 上海有机化学研究所_生命有机化学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Ma DW,Wu WG,Yang GX,et al. Tetrahydroisoquinoline based sulfonamide hydroxamates as potent matrix metalloproteinase inhibitors[J]. Bioorg. Med. Chem. Lett.,2004,14(1):47-50. |
| APA | 马大为,吴问根,杨国新,LI JINGYA,李佳,&叶其壮.(2004).Tetrahydroisoquinoline based sulfonamide hydroxamates as potent matrix metalloproteinase inhibitors.Bioorg. Med. Chem. Lett.,14(1),47-50. |
| MLA | 马大为,et al."Tetrahydroisoquinoline based sulfonamide hydroxamates as potent matrix metalloproteinase inhibitors".Bioorg. Med. Chem. Lett. 14.1(2004):47-50. |
入库方式： OAI收割
来源：上海有机化学研究所
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