Construction of hollow DNA/PLL microcapsule as a dual carrier for controlled delivery of DNA and drug
文献类型：期刊论文
| 作者 | Wang ZJ ; Qian L ; Wang XL ; Yang F ; Yang XR |
| 刊名 | colloids and surfaces a-physicochemical and engineering aspects
 |
| 出版日期 | 2008 |
| 卷号 | 326期号:1-2页码:29-36 |
| 关键词 | POLYELECTROLYTE MULTILAYER CAPSULES BIODEGRADABLE MICROCAPSULES GENE-THERAPY CARBONATE MICROPARTICLES MEDIATED TRANSFECTION CONTROLLED-RELEASE NUCLEIC-ACIDS NANOPARTICLES FILMS ENCAPSULATION |
| ISSN号 | 0927-7757 |
| 通讯作者 | yang xr |
| 中文摘要 | dna/poly-l-lysine (pll) capsules were constructed through a layer-by-layer (lbl) self-assembly of dna and pll on caco3 microparticles, and then used as dual carriers for dna and drug after dissolution of carbonate cores. the permeability of dna/pll microcapsules was investigated with fluorescence probes with different molecular weights by confocal microscopy. the result revealed that the fluorescence probes were able to penetrate the capsule walls even its molecular weight up to 150 kda. the resultant capsules were used to load drug model molecules-fluorescein isothiocyanate (fitc)-dextran (4 kda) via spontaneous deposition mechanism. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000259523100005 |
| 公开日期 | 2010-04-14 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/10557]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Wang ZJ,Qian L,Wang XL,et al. Construction of hollow DNA/PLL microcapsule as a dual carrier for controlled delivery of DNA and drug[J]. colloids and surfaces a-physicochemical and engineering aspects,2008,326(1-2):29-36. |
| APA | Wang ZJ,Qian L,Wang XL,Yang F,&Yang XR.(2008).Construction of hollow DNA/PLL microcapsule as a dual carrier for controlled delivery of DNA and drug.colloids and surfaces a-physicochemical and engineering aspects,326(1-2),29-36. |
| MLA | Wang ZJ,et al."Construction of hollow DNA/PLL microcapsule as a dual carrier for controlled delivery of DNA and drug".colloids and surfaces a-physicochemical and engineering aspects 326.1-2(2008):29-36. |
入库方式： OAI收割
来源：长春应用化学研究所
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