Fluorophore-appended steroidal saponin (Dioscin and Polyphyllin D) derivatives
文献类型:期刊论文
作者 | Yang ZQ(杨志奇) ; WONG ELLA LAIMING ; SHUM TINA YUEN-TING ; Zhi ZM(支志明) ; Hui YZ(惠永正) |
刊名 | Org. Lett. |
出版日期 | 2005 |
卷号 | 7期号:4页码:669-672 |
ISSN号 | 1523-7060 |
其他题名 | Fluorophore-appended steroidal saponin (Dioscin and Polyphyllin D) derivatives |
通讯作者 | 支志明 ; 惠永正 |
英文摘要 | The synthesis of three fluorophore-appended derivatives of dioscin and polyphyllin D is reported herein. Starting from trillin, dansyl derivatives A-C were prepared in overall yields of 7-12% over 7-10 steps. A study of their behavior in a variety of polar solvents suggests that dansyl derivatives A-C are capable of micellar self-assembly and can maintain cytotoxicities (IC50 = 15-18 muM) against the HeLa carcinoma cell line evaluated by standard MTT assay. |
学科主题 | 生命有机化学 ; 氟化学 |
收录类别 | SCI |
原文出处 | http://dx.doi.org/10.1021/ol0475616 |
语种 | 英语 |
WOS记录号 | WOS:000226950100037 |
公开日期 | 2013-02-25 |
源URL | [http://202.127.28.38/handle/331003/19521] |
专题 | 上海有机化学研究所_生命有机化学国家重点实验室 |
推荐引用方式 GB/T 7714 | Yang ZQ,WONG ELLA LAIMING,SHUM TINA YUEN-TING,et al. Fluorophore-appended steroidal saponin (Dioscin and Polyphyllin D) derivatives[J]. Org. Lett.,2005,7(4):669-672. |
APA | 杨志奇,WONG ELLA LAIMING,SHUM TINA YUEN-TING,支志明,&惠永正.(2005).Fluorophore-appended steroidal saponin (Dioscin and Polyphyllin D) derivatives.Org. Lett.,7(4),669-672. |
MLA | 杨志奇,et al."Fluorophore-appended steroidal saponin (Dioscin and Polyphyllin D) derivatives".Org. Lett. 7.4(2005):669-672. |
入库方式: OAI收割
来源:上海有机化学研究所
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