Conformational isomerization of N-(napthalen-1-yl)-N-(phenyl(quinolin-3-yl)methyl)amide derivatives
文献类型：期刊论文
| 作者 | Cai ZQ(蔡志强) ; Zhu CJ(朱传钧) ; Cui YX(崔育新) ; Jiang B(姜标) ; Sun TM(孙铁民) |
| 刊名 | Sci. China Ser. B-Chem.
 |
| 出版日期 | 2009 |
| 卷号 | 52期号:12页码:2051-2054 |
| ISSN号 | 1674-7291 |
| 其他题名 | N-(萘-1-基)-N-(苯基(喹啉-3-基)甲基)胺衍生物的构象异构研究 |
| 通讯作者 | 姜标 ; 孙铁民 |
| 英文摘要 | A series of N-(naphthalen-1-yl)-N-(phenyl(quinolin-3-yl)methyl)amide derivatives were designed and synthesized as anti-Mycobacterium tuberculosis drugs. NMR spectra showed that two conformational isomers of these compounds exist in solution, which is not due to cis-trans isomerization of amide bond. We proposed that the spatial interactions between three large aromatic groups caused the conformational isomerization, which was supported by molecular modeling and X-ray diffraction. |
| 学科主题 | 天然产物有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1007/s11426-009-0181-1 |
| 语种 | 英语 |
| 公开日期 | 2013-02-25 |
| 源URL | [http://202.127.28.38/handle/331003/20281]  |
| 专题 | 上海有机化学研究所_中科院天然产物有机化学重点实验室 |
| 推荐引用方式 GB/T 7714 | Cai ZQ,Zhu CJ,Cui YX,et al. Conformational isomerization of N-(napthalen-1-yl)-N-(phenyl(quinolin-3-yl)methyl)amide derivatives[J]. Sci. China Ser. B-Chem.,2009,52(12):2051-2054. |
| APA | 蔡志强,朱传钧,崔育新,姜标,&孙铁民.(2009).Conformational isomerization of N-(napthalen-1-yl)-N-(phenyl(quinolin-3-yl)methyl)amide derivatives.Sci. China Ser. B-Chem.,52(12),2051-2054. |
| MLA | 蔡志强,et al."Conformational isomerization of N-(napthalen-1-yl)-N-(phenyl(quinolin-3-yl)methyl)amide derivatives".Sci. China Ser. B-Chem. 52.12(2009):2051-2054. |
入库方式： OAI收割
来源：上海有机化学研究所
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