题名: Selective synthesis of poly-substituted fluorine-containing pyridines and dihydropyrimidines via cascade C-F bond cleavage protocol
作者: Chen ZX(陈资衔) ; Zhu JT(祝江涛) ; Xie HB(谢海波) ; Li S(李删) ; Wu YM(吴永明) ; Gong YF(龚跃发)
刊名: Org. Biomol. Chem.
出版日期: 2011
卷号: 9, 期号:16, 页码:5682-5691
其他题名: 通过串联的C-F键断裂策略, 选择性合成含氟多取代吡啶和二氢嘧啶类化合物
通讯作者: 吴永明 ; 龚跃发
英文摘要: Fluorinated azaheterocycles are frequently found in pharmaceuticals, drug candidates, ligands for transition metal catalysts, and other molecular functional materials, so efficient methods for the synthesis of these compounds are of significant value. We herein describe a selective strategy for the synthesis of poly-substituted pyridines and fluoroalkyl dihydropyrimidines based on C-F bond breaking of the anionically activated fluoroalkyl group. An array of pyridines and dihydropyrimidines were prepared through this domino process in high yields under noble metal catalyst-free conditions, making this method a valuable supplement to azaheterocycle synthesis.
收录类别: SCI
原文出处: 查看原文
语种: 英语
WOS记录号: WOS:000293230300013
Citation statistics:
内容类型: 期刊论文
URI标识: [http://202.127.28.38/handle/331003/25169]  
Appears in Collections:中科院有机氟化学重点实验室_期刊论文


Recommended Citation:
陈资衔; 祝江涛; 谢海波; 李删; 吴永明; 龚跃发.Selective synthesis of poly-substituted fluorine-containing pyridines and dihydropyrimidines via cascade C-F bond cleavage protocol,Org. Biomol. Chem.,2011,9(16):5682-5691
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[陈资衔]'s Articles
[祝江涛]'s Articles
[谢海波]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[陈资衔]‘s Articles
[祝江涛]‘s Articles
[谢海波]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
版权所有@2017 - 中国科学院  运行维护:中国科学院兰州文献情报中心
Powered by CSpace