Chiral metallo-supramolecular complexes selectively recognize human telomeric G-quadruplex DNA
文献类型：期刊论文
| 作者 | Yu HJ ; Wang XH ; Fu ML ; Ren JS ; Qu XG |
| 刊名 | nucleic acids research
 |
| 出版日期 | 2008 |
| 卷号 | 36期号:17页码:5695-5703 |
| 关键词 | METALLOSUPRAMOLECULAR CYLINDERS G-TETRAPLEX BINDING RESOLUTION SEQUENCE STABILIZATION INHIBITION HYDRATION LIGANDS K+ |
| ISSN号 | 0305-1048 |
| 通讯作者 | qu xg |
| 中文摘要 | here, we report the first example that one enantiomer of a supramolecular cylinder can selectively stabilize human telomeric g-quadruplex dna. the p-enantiomer of this cylinder has a strong preference for g-quadruplex over duplex dna and, in the presence of sodium, can convert g-quadruplexes from an antiparallel to a hybrid structure. the compound's chiral selectivity and its ability to discriminate quadruplex dna have been studied by dna melting, circular dichroism, gel electrophoresis, fluorescence spectroscopy and s1 nuclease cleavage. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000260424200024 |
| 公开日期 | 2010-04-14 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/10825]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Yu HJ,Wang XH,Fu ML,et al. Chiral metallo-supramolecular complexes selectively recognize human telomeric G-quadruplex DNA[J]. nucleic acids research,2008,36(17):5695-5703. |
| APA | Yu HJ,Wang XH,Fu ML,Ren JS,&Qu XG.(2008).Chiral metallo-supramolecular complexes selectively recognize human telomeric G-quadruplex DNA.nucleic acids research,36(17),5695-5703. |
| MLA | Yu HJ,et al."Chiral metallo-supramolecular complexes selectively recognize human telomeric G-quadruplex DNA".nucleic acids research 36.17(2008):5695-5703. |
入库方式： OAI收割
来源：长春应用化学研究所
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