Toxicological effects of cinnabar in rats by NMR-based metabolic profiling of urine and serum
文献类型：期刊论文
| 作者 | Wei L ; Liao PQ ; Wu HF ; Li XJ ; Pei FK ; Li WS ; Wu YJ |
| 刊名 | toxicology and applied pharmacology
 |
| 出版日期 | 2008 |
| 卷号 | 227期号:3页码:417-429 |
| 关键词 | MAGNETIC-RESONANCE-SPECTROSCOPY LIVER TAURINE LEVELS PATTERN-RECOGNITION OXIDATIVE STRESS MERCURIC SULFIDE HEPATOTOXIC COMPOUNDS SYSTEMS BIOLOGY DRUG TOXICITY RENAL DAMAGE METABONOMICS |
| ISSN号 | 0041-008x |
| 通讯作者 | li xj |
| 中文摘要 | cinnabar, an important traditional chinese mineral medicine, has been widely used as a chinese patent medicine ingredient for sedative therapy. however, the pharmaceutical and toxicological effects of cinnabar, especially in the whole organism, were subjected to few investigations. in this study, an nmr-based metabolomics approach has been applied to investigate the toxicological effects of cinnabar after intragastrical administration (dosed at 0.5, 2 and 5 g/kg body weight) on male wistar rats. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000254090500010 |
| 公开日期 | 2010-04-14 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/10935]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Wei L,Liao PQ,Wu HF,et al. Toxicological effects of cinnabar in rats by NMR-based metabolic profiling of urine and serum[J]. toxicology and applied pharmacology,2008,227(3):417-429. |
| APA | Wei L.,Liao PQ.,Wu HF.,Li XJ.,Pei FK.,...&Wu YJ.(2008).Toxicological effects of cinnabar in rats by NMR-based metabolic profiling of urine and serum.toxicology and applied pharmacology,227(3),417-429. |
| MLA | Wei L,et al."Toxicological effects of cinnabar in rats by NMR-based metabolic profiling of urine and serum".toxicology and applied pharmacology 227.3(2008):417-429. |
入库方式： OAI收割
来源：长春应用化学研究所
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