Interactions of mitoxantrone with duplex and triplex DNA studied by electrospray ionization mass spectrometry
文献类型：期刊论文
| 作者 | Wan CH ; Guo XH ; Song FR ; Liu ZQ ; Liu SY |
| 刊名 | rapid communications in mass spectrometry
 |
| 出版日期 | 2008 |
| 卷号 | 22期号:24页码:4043-4048 |
| 关键词 | DOUBLE-STRANDED OLIGODEOXYNUCLEOTIDES NONCOVALENT COMPLEXES SEQUENCE SPECIFICITY NUCLEIC-ACIDS FTICR-MS ESI-MS BINDING LIGANDS DRUGS ANTHRAPYRAZOLES |
| ISSN号 | 0951-4198 |
| 通讯作者 | liu sy |
| 中文摘要 | we have examined interactions between mitoxantrone (mxt) and dna duplexes or triplexes with different base compositions by using electrospray ionization mass spectrometry (esi-ms), respectively. mxt interacts preferentially with dna duplexes compared to the triplexes. in the mass spectrum of the duplex-mxt mixture, the complex peaks dominated in the ratios of duplex/mxt of 1:1, 1:2 and 1:3, and the 1:2 duplex/mxt peak was the most abundant. in contrast, only 1:1 triplex-mxt complexes were observed in the mass spectrum of the triplex-mxt mixture, and the most intensive peak was a free triplex ion without mxt. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000262293100009 |
| 公开日期 | 2010-04-14 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/10937]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Wan CH,Guo XH,Song FR,et al. Interactions of mitoxantrone with duplex and triplex DNA studied by electrospray ionization mass spectrometry[J]. rapid communications in mass spectrometry,2008,22(24):4043-4048. |
| APA | Wan CH,Guo XH,Song FR,Liu ZQ,&Liu SY.(2008).Interactions of mitoxantrone with duplex and triplex DNA studied by electrospray ionization mass spectrometry.rapid communications in mass spectrometry,22(24),4043-4048. |
| MLA | Wan CH,et al."Interactions of mitoxantrone with duplex and triplex DNA studied by electrospray ionization mass spectrometry".rapid communications in mass spectrometry 22.24(2008):4043-4048. |
入库方式： OAI收割
来源：长春应用化学研究所
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