Chiral ligand 2-(2 '-piperidinyl)pyridine: synthesis, resolution and application in asymmetric diethylzinc addition to aldehydes
文献类型：期刊论文
| 作者 | Cheng YQ ; Bian Z ; Kang CQ ; Guo HQ ; Gao LX |
| 刊名 | tetrahedron-asymmetry
 |
| 出版日期 | 2008 |
| 卷号 | 19期号:13页码:1572-1575 |
| 关键词 | BETA-AMINO ALCOHOLS ENANTIOSELECTIVE ADDITION LITHIATION-SUBSTITUTION ALLYLIC SUBSTITUTION COMPLEXES CATALYSIS BIPYRIDINES REDUCTION 2-<(2S)-2-PYRROLIDINYL>PYRIDINE COORDINATION |
| ISSN号 | 0957-4166 |
| 通讯作者 | gao lx |
| 中文摘要 | chiral ligand 2-(2'-piperidinyl)pyridine 1 has been synthesized in good overall yield by sequential benzylation, hydrogenation and debenzylation of 2,2'-bipyridine. its enantiomerically pure enantiomers have been obtained by resolution of 2-(1-benzyl-2-piperidinyl)pyridine 2 with d-tartaric acid (or l-tartaric acid) followed by debenzylation. the absolute configuration was determined by x-ray analysis of the (s)-2 d-tartrate. it was demonstrated that i can be used as an effective enantioselective catalyst in the addition of diethylzinc to aldehydes. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000258433400009 |
| 公开日期 | 2010-04-14 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/11073]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Cheng YQ,Bian Z,Kang CQ,et al. Chiral ligand 2-(2 '-piperidinyl)pyridine: synthesis, resolution and application in asymmetric diethylzinc addition to aldehydes[J]. tetrahedron-asymmetry,2008,19(13):1572-1575. |
| APA | Cheng YQ,Bian Z,Kang CQ,Guo HQ,&Gao LX.(2008).Chiral ligand 2-(2 '-piperidinyl)pyridine: synthesis, resolution and application in asymmetric diethylzinc addition to aldehydes.tetrahedron-asymmetry,19(13),1572-1575. |
| MLA | Cheng YQ,et al."Chiral ligand 2-(2 '-piperidinyl)pyridine: synthesis, resolution and application in asymmetric diethylzinc addition to aldehydes".tetrahedron-asymmetry 19.13(2008):1572-1575. |
入库方式： OAI收割
来源：长春应用化学研究所
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