Chroman-4-one and pyrano[4,3-b] chromenone derivatives from the mangrove endophytic fungus Diaporthe phaseolorum SKS019
文献类型：期刊论文
| 作者 | Cui, H; Ding, M; Huang, DN; Zhang, ZR; Liu, HT; Huang, HB; She, ZG |
| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2017 |
| 卷号 | 7期号:33页码:20128-20134 |
| 通讯作者 | huanghb@scsio.ac.cn ; cesshzhg@mail.sysu.edu.cn |
| 中文摘要 | Seven new compounds: diaporchromanones A-D (1-4), (-)-phomopsichin A (5a), (+)-phomopsichin B (6a), and (-)-diaporchromone A (7), along with the known (+)-phomopsichin A (5b) and (-)-phomopsichin B (6b) were isolated from an endophytic fungus Diaporthe phaseolorum SKS019. The structures of the new compounds, including their absolute configurations, were determined on the basis of HRESIMS and NMR spectroscopic data, and experimental ECD and Rh-2(OCOCF3)(4) induced CD spectra analyses. Diaporchromanone A (1)/B (2), and C (3)/D (4) are two pairs of 3-epimers, and their structures possessing 3-substituted-chroman-4-one skeleton are rarely found in natural sources. (-)-Phomopsichin A (5a) and (+)-phomopsichin B (6a) are enantiomers of (+)-phomopsichin A (5b) and (-)-phomopsichin B (6b), respectively. All of the isolates were evaluated for their inhibitory effects against osteoclastogenesis in the RAW 264.7 cell line using luciferase reporter gene assays. Compounds 3-6b exhibited moderate inhibitory effects on osteoclastogenesis by suppressing the receptor activator of NF-kappa B by ligand-induced NF-kappa B activation. |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/16220]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 推荐引用方式 GB/T 7714 | Cui, H,Ding, M,Huang, DN,et al. Chroman-4-one and pyrano[4,3-b] chromenone derivatives from the mangrove endophytic fungus Diaporthe phaseolorum SKS019[J]. RSC ADVANCES,2017,7(33):20128-20134. |
| APA | Cui, H.,Ding, M.,Huang, DN.,Zhang, ZR.,Liu, HT.,...&She, ZG.(2017).Chroman-4-one and pyrano[4,3-b] chromenone derivatives from the mangrove endophytic fungus Diaporthe phaseolorum SKS019.RSC ADVANCES,7(33),20128-20134. |
| MLA | Cui, H,et al."Chroman-4-one and pyrano[4,3-b] chromenone derivatives from the mangrove endophytic fungus Diaporthe phaseolorum SKS019".RSC ADVANCES 7.33(2017):20128-20134. |
入库方式： OAI收割
来源：南海海洋研究所
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