Brevianamides and Mycophenolic Acid Derivatives from the Deep-Sea-Derived Fungus Penicillium brevicompactum DFFSCS025
文献类型：期刊论文
| 作者 | Xu, XY; Zhang, XY; Nong, XH; Wang, J; Qi, SH |
| 刊名 | MARINE DRUGS
 |
| 出版日期 | 2017 |
| 卷号 | 15期号:2页码:43- |
| 关键词 | Penicillium brevicompactum Brevianamide Mycochromenic acid derivative cytotoxicity antifouling |
| 通讯作者 | xuxinya@scsio.ac.cn ; zhangxiaoyong@scsio.ac.cn ; xhnong@scsio.ac.cn ; wangjielangjing@126.com ; shuhuaqi@scsio.ac.cn |
| 中文摘要 | Four new compounds (1-4), including two brevianamides and two mycochromenic acid derivatives along with six known compounds were isolated from the deep-sea-derived fungus Penicillium brevicompactum DFFSCS025. Their structures were elucidated by spectroscopic analysis. Moreover, the absolute configurations of 1 and 2 were determined by quantum chemical calculations of the electronic circular dichroism (ECD) spectra. Compound 9 showed moderate cytotoxicity against human colon cancer HCT116 cell line with IC50 value of 15.6 mu M. In addition, 3 and 5 had significant antifouling activity against Bugula neritina larval settlement with EC50 values of 13.7 and 22.6 mu M, respectively. The NMR data of 6, 8, and 9 were assigned for the first time. |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/16237]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 推荐引用方式 GB/T 7714 | Xu, XY,Zhang, XY,Nong, XH,et al. Brevianamides and Mycophenolic Acid Derivatives from the Deep-Sea-Derived Fungus Penicillium brevicompactum DFFSCS025[J]. MARINE DRUGS,2017,15(2):43-. |
| APA | Xu, XY,Zhang, XY,Nong, XH,Wang, J,&Qi, SH.(2017).Brevianamides and Mycophenolic Acid Derivatives from the Deep-Sea-Derived Fungus Penicillium brevicompactum DFFSCS025.MARINE DRUGS,15(2),43-. |
| MLA | Xu, XY,et al."Brevianamides and Mycophenolic Acid Derivatives from the Deep-Sea-Derived Fungus Penicillium brevicompactum DFFSCS025".MARINE DRUGS 15.2(2017):43-. |
入库方式： OAI收割
来源：南海海洋研究所
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