Antiviral peptides from marine gorgonian-derived fungus Aspergillus sp SCSIO 41501
文献类型：期刊论文
| 作者 | Ma, X; Nong, XH; Ren, Z; Wang, J; Liang, X; Wang, L; Qi, SH |
| 刊名 | TETRAHEDRON LETTERS
 |
| 出版日期 | 2017 |
| 卷号 | 58期号:12页码:1151-1155 |
| 关键词 | Gorgonian-derived fungus Aspergillus sp. Peptide Antiviral |
| 通讯作者 | shuhuaqi@scsio.ac.cn |
| 中文摘要 | A new cyclic pentapeptide and three new linear peptides, namely, aspergillipeptides D-G (1-4), were isolated from a culture broth of marine gorgonian-derived fungus Aspergillus sp. SCSIO 41501. Their structures were elucidated by spectroscopic analysis, and their absolute configurations were confirmed by Marfey's method. Compounds 1 and 2 showed evident antiviral activity against herpes simplex virus type 1 (HSV-1) with IC50 values of 9.5 and 19.8 mu M under their non-cytotoxic concentrations against a Vero cell line, respectively, and 1 also had antiviral activity against acyclovir-resistant clinical isolates of HSV-1. (C) 2017 Elsevier Ltd. All rights reserved. |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/16254]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 推荐引用方式 GB/T 7714 | Ma, X,Nong, XH,Ren, Z,et al. Antiviral peptides from marine gorgonian-derived fungus Aspergillus sp SCSIO 41501[J]. TETRAHEDRON LETTERS,2017,58(12):1151-1155. |
| APA | Ma, X.,Nong, XH.,Ren, Z.,Wang, J.,Liang, X.,...&Qi, SH.(2017).Antiviral peptides from marine gorgonian-derived fungus Aspergillus sp SCSIO 41501.TETRAHEDRON LETTERS,58(12),1151-1155. |
| MLA | Ma, X,et al."Antiviral peptides from marine gorgonian-derived fungus Aspergillus sp SCSIO 41501".TETRAHEDRON LETTERS 58.12(2017):1151-1155. |
入库方式： OAI收割
来源：南海海洋研究所
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