含二硫键多肽的基质辅助激光解析电离飞行时间质谱研究
文献类型：期刊论文
| 作者 | 仇小燕 ; 崔勐 ; 宋凤瑞 ; 刘志强 ; 刘淑莹 |
| 刊名 | 质谱学报
 |
| 出版日期 | 2008 |
| 卷号 | 29增刊页码:96-97 |
| 关键词 | MALDI-MS disulfide bond prompt fragment |
| ISSN号 | 1004-2997 |
| 通讯作者 | 刘志强 |
| 中文摘要 | The determination of disulfide bonds becomes an important aspect of obtaining a comprehensive understanding of the chemical structure of a protein. Numerous experimental methods have been developed for the determination of disulfide bonds in proteins. Modern mass spectrometry has developed as an important tool for the analysis of disulfide bond patterns due to its advantages of being simple, rapid and sensitive. The dissociations of the disulfide bonds were detected during the matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) analysis. These fragment ions were attributed to prompt fragmentation or “in-source decay” rather than “post-source decay”. For the double disulfide bonds, ions of plus sulfur and minus sulfur atoms corresponding to cleavages at different sites within the carbon-sulfur-sulfur-carbon disulfide bonds were also observed. |
| 收录类别 | CSCD收录国内期刊论文 |
| 语种 | 中文 |
| 公开日期 | 2010-04-14 ; 2011-06-09 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/11159]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | 仇小燕,崔勐,宋凤瑞,等. 含二硫键多肽的基质辅助激光解析电离飞行时间质谱研究[J]. 质谱学报,2008,29增刊:96-97. |
| APA | 仇小燕,崔勐,宋凤瑞,刘志强,&刘淑莹.(2008).含二硫键多肽的基质辅助激光解析电离飞行时间质谱研究.质谱学报,29增刊,96-97. |
| MLA | 仇小燕,et al."含二硫键多肽的基质辅助激光解析电离飞行时间质谱研究".质谱学报 29增刊(2008):96-97. |
入库方式： OAI收割
来源：长春应用化学研究所
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