Hollow DNA/PLL microcapsules with tunable degradation property as efficient dual drug delivery vehicles by alpha-chymotrypsin degradation
文献类型：期刊论文
| 作者 | Wang ZJ ; Qian L ; Wang XL ; Zhu H ; Yang F ; Yang XR |
| 刊名 | colloids and surfaces a-physicochemical and engineering aspects
 |
| 出版日期 | 2009 |
| 卷号 | 332期号:2-3页码:164-171 |
| 关键词 | POLYELECTROLYTE MULTILAYER MICROCAPSULES SUSTAINED-RELEASE BIODEGRADABLE MICROCAPSULES DNA DELIVERY THIN-FILMS IN-VIVO CAPSULES ENCAPSULATION CONSTRUCTION CHITOSAN |
| ISSN号 | 0927-7757 |
| 通讯作者 | yang xr |
| 中文摘要 | hollow deoxyribonucleic acid (dna)/poly-l-lysine (pll) capsules were successfully fabricated through a layer-by-layer (lbl) self-assembly of dna and pll on porous caco3 microparticles, followed by removal of templates with ethylenediamine tetraacetic acid disodium salt (edta). the enzymatic degradation of the capsules in the presence of alpha-chymotrypsin was explored. the higher the enzyme concentration, the higher is the degradation rate of hollow capsules. in addition, glutaric dialdehyde (ga) cross-linking was found to be another way to manipulate degradation rate of hollow capsules. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000262119900014 |
| 公开日期 | 2010-05-04 |
| 源URL | [http://202.98.16.49/handle/322003/11215]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Wang ZJ,Qian L,Wang XL,et al. Hollow DNA/PLL microcapsules with tunable degradation property as efficient dual drug delivery vehicles by alpha-chymotrypsin degradation[J]. colloids and surfaces a-physicochemical and engineering aspects,2009,332(2-3):164-171. |
| APA | Wang ZJ,Qian L,Wang XL,Zhu H,Yang F,&Yang XR.(2009).Hollow DNA/PLL microcapsules with tunable degradation property as efficient dual drug delivery vehicles by alpha-chymotrypsin degradation.colloids and surfaces a-physicochemical and engineering aspects,332(2-3),164-171. |
| MLA | Wang ZJ,et al."Hollow DNA/PLL microcapsules with tunable degradation property as efficient dual drug delivery vehicles by alpha-chymotrypsin degradation".colloids and surfaces a-physicochemical and engineering aspects 332.2-3(2009):164-171. |
入库方式： OAI收割
来源：长春应用化学研究所
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