Multiplex binding modes of toluidine blue with calf thymus DNA and conformational transition of DNA revealed by spectroscopic studies
文献类型：期刊论文
| 作者 | Wang J ; Yang XR |
| 刊名 | spectrochimica acta part a-molecular and biomolecular spectroscopy
 |
| 出版日期 | 2009 |
| 卷号 | 74期号:2页码:421-426 |
| 关键词 | SURFACE-ENHANCED RAMAN METHYLENE-BLUE NUCLEIC-ACIDS NONCOVALENT INTERACTIONS SILVER FLUORESCENCE ADSORPTION SCATTERING PORPHYRIN THIONINE |
| ISSN号 | 1386-1425 |
| 通讯作者 | yang xr |
| 中文摘要 | it is noteworthy to understand the details of interactions between antitumor drugs and dna because the binding modes and affinities affect their antitumor activities. here, the interaction of toluidine blue (tb), a potential antitumor drug for photodynamic therapy of tumor, with calf thymus dna (ctdna) was explored by uv-vis, fluorescence, circular dichroism (cd) spectroscopy, uv-rnelting method and surface-enhance raman spectroscopy (sers). the experimental results suggest that tb could bind to ctdna via both electrostatic interaction and partial intercalation. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000270109300018 |
| 公开日期 | 2010-05-04 |
| 源URL | [http://202.98.16.49/handle/322003/11223]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Wang J,Yang XR. Multiplex binding modes of toluidine blue with calf thymus DNA and conformational transition of DNA revealed by spectroscopic studies[J]. spectrochimica acta part a-molecular and biomolecular spectroscopy,2009,74(2):421-426. |
| APA | Wang J,&Yang XR.(2009).Multiplex binding modes of toluidine blue with calf thymus DNA and conformational transition of DNA revealed by spectroscopic studies.spectrochimica acta part a-molecular and biomolecular spectroscopy,74(2),421-426. |
| MLA | Wang J,et al."Multiplex binding modes of toluidine blue with calf thymus DNA and conformational transition of DNA revealed by spectroscopic studies".spectrochimica acta part a-molecular and biomolecular spectroscopy 74.2(2009):421-426. |
入库方式： OAI收割
来源：长春应用化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。