Effects of pyrene exposure on immune response and oxidative stress in the pearl oyster, Pinctada martensii
文献类型：期刊论文
| 作者 | Xie, Jia1,2,3; Zhao, Chunfeng1,2; Han, Qian1,2; Zhou, Hailong1,2; Li, Qingxiao4; Diao, Xiaoping1,2 |
| 刊名 | FISH & SHELLFISH IMMUNOLOGY
 |
| 出版日期 | 2017-04-01 |
| 卷号 | 63页码:237-244 |
| 关键词 | Pinctada martensii Hemocyte Pyrene Immunotoxicity Oxidative stress |
| ISSN号 | 1050-4648 |
| 产权排序 | [Xie, Jia; Zhao, Chunfeng; Han, Qian; Zhou, Hailong; Diao, Xiaoping] Hainan Univ, State Key Lab South China Sea Marine Resource Uti, Haikou 570228, Peoples R China; [Xie, Jia; Zhao, Chunfeng; Han, Qian; Zhou, Hailong; Diao, Xiaoping] Hainan Univ, Inst Trop Agr & Forestry, 58 Renmin Rd, Haikou 570228, Hainan, Peoples R China; [Xie, Jia] Chinese Acad Sci, Yantai Inst Coastal Zone Res, 17,Chunhui Rd, Laishan Dist 264003, Yantai, Peoples R China; [Li, Qingxiao] Univ Hawaii Manoa, Dept Mol Biosci & Bioengn, 1955 East West Rd, Honolulu, HI 96822 USA |
| 通讯作者 | Zhou, HL |
| 英文摘要 | Pyrene is a polycyclic aromatic hydrocarbon (PAH) commonly observed in. aquatic ecosystems, which originates primarily from the incomplete combustion of fossil fuels and the use of petroleum compounds. Pyrene can cause the immune disturbance and oxidative stress, result in immunotoxicity, DNA damage, reduce reproduction significantly, and induce behavioral changes. Marine bivalves are commonly used as bioindicators for marine pollution, and hemolymph is a metabolite transfer medium for PAH pollutant. However, the vital immune indicator responses of pearl oyster Pinctada martensii hemolymph exposed to pyrene is still unclear. Thus, the immunotoxic responses of pyrene on the hemolymph of the Pinctada martensii were investigated in this study. After exposure to pyrene for 7 days, the total number of hemocytes (THC), cell membrane stability (CMS), phagocytic activity (PA) and total glutathione (GSHT) all decreased significantly. Pyrene also caused a significant increase in lipid peroxidation (LPO). Median effective concentrations (EC50) of pyrene on THC (4.5 mu g L-1) and LPO (5.2 mu g L-1) were lower than those for CMS (13.8 mu g L-1), PA (12.1 mu g L-1) and GSHT (7.2 mu g L-1), which indicates that THC and LPO were more sensitive. Additionally, a clear dose-effect relationship indicated that pyrene stimulated a marked immune response, as well as oxidative stress in P. martensii, which demonstrates the subtle effects of pyrene exposure on marine invertebrates and the potential associated risk. (C) 2017 Elsevier Ltd. All rights reserved. |
| 学科主题 | Fisheries ; Immunology ; Marine & Freshwater Biology ; Veterinary Sciences |
| 研究领域[WOS] | Fisheries ; Immunology ; Marine & Freshwater Biology ; Veterinary Sciences |
| 关键词[WOS] | POLYCYCLIC AROMATIC-HYDROCARBONS ; MUSSEL MYTILUS-EDULIS ; ECOLOGICAL RISK-ASSESSMENT ; MARINE MUSSEL ; OIL-SPILL ; HALIOTIS-DIVERSICOLOR ; CRASSOSTREA-GIGAS ; BIVALVE IMMUNITY ; PACIFIC OYSTER ; YANGPU BAY |
| 收录类别 | SCI |
| 原文出处 | 10.1016/j.fsi.2017.02.032 |
| 语种 | 英语 |
| WOS记录号 | WOS:000398870700026 |
| 源URL | [http://ir.yic.ac.cn/handle/133337/22096]  |
| 专题 | 烟台海岸带研究所_中科院烟台海岸带研究所知识产出 |
| 作者单位 | 1.Hainan Univ, State Key Lab South China Sea Marine Resource Uti, Haikou 570228, Peoples R China 2.Hainan Univ, Inst Trop Agr & Forestry, 58 Renmin Rd, Haikou 570228, Hainan, Peoples R China 3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, 17,Chunhui Rd, Laishan Dist 264003, Yantai, Peoples R China 4.Univ Hawaii Manoa, Dept Mol Biosci & Bioengn, 1955 East West Rd, Honolulu, HI 96822 USA |
| 推荐引用方式 GB/T 7714 | Xie, Jia,Zhao, Chunfeng,Han, Qian,et al. Effects of pyrene exposure on immune response and oxidative stress in the pearl oyster, Pinctada martensii[J]. FISH & SHELLFISH IMMUNOLOGY,2017,63:237-244. |
| APA | Xie, Jia,Zhao, Chunfeng,Han, Qian,Zhou, Hailong,Li, Qingxiao,&Diao, Xiaoping.(2017).Effects of pyrene exposure on immune response and oxidative stress in the pearl oyster, Pinctada martensii.FISH & SHELLFISH IMMUNOLOGY,63,237-244. |
| MLA | Xie, Jia,et al."Effects of pyrene exposure on immune response and oxidative stress in the pearl oyster, Pinctada martensii".FISH & SHELLFISH IMMUNOLOGY 63(2017):237-244. |
入库方式： OAI收割
来源：烟台海岸带研究所
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