Lectin functionalized ZnO nanoarrays as a 3D nano-biointerface for bacterial detection
文献类型：期刊论文
| 作者 | Zheng, Laibao1,2 ; Wan, Yi1; Qi, Peng1; Sun, Yan1; Zhang, Dun1; Yu, Liangmin3,4
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| 刊名 | TALANTA
 |
| 出版日期 | 2017-05-15 |
| 卷号 | 167页码:600-606 |
| 关键词 | 3D nano-interface ZnO-NR arrays Lectin functionalization Bacterial detection |
| 英文摘要 | The detection of pathogenic bacteria is essential in various fields, such as food safety, water environmental analysis, or clinical diagnosis. Although rapid and selective techniques have been achieved based on the fast and specific binding of recognitions elements and target, the sensitive detection of bacterial pathogens was limited by their low targets-binding efficiency. The three-dimensional (3D) nano-biointerface, compared with the two-dimensional (2D) flat substrate, has a much higher binding capacity, which can offer more reactive sites to bind with bacterial targets, resulting in a great improvement of detection sensitivity. Herein, a lectin functionalized ZnO nanorod (ZnO-NR) array has been fabricated and employed as a 3D nano-biointerface for Escherichia coli (E. con) capture and detection by multivalent binding of concanavalin A (ConA) with polysaccharides on the cellular surface of E. coli. The 3D lectin functionalized ZnO-NR array-based assay shows reasonable detection limit and efficiently expanded linear range (1.0x10(3) to 1.0x10(7) cfu mL(-1)) for pathogen detection. The platform has a potential for further applications and provides an excellent sensitivity approach for detection of pathogenic bacteria. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000399511600075 |
| 版本 | 出版稿 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/136699]  |
| 专题 | 海洋研究所_海洋腐蚀与防护研究发展中心 |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Marine Environm Corros & Biofouling, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China 3.Ocean Univ China, Key Lab Marine Chem Theory & Technol, Minist Educ, Qingdao 266100, Peoples R China 4.Ocean Univ China, Qingdao Collaborat Innovat Ctr Marine Sci & Techn, Qingdao 266100, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zheng, Laibao,Wan, Yi,Qi, Peng,et al. Lectin functionalized ZnO nanoarrays as a 3D nano-biointerface for bacterial detection[J]. TALANTA,2017,167:600-606. |
| APA | Zheng, Laibao,Wan, Yi,Qi, Peng,Sun, Yan,Zhang, Dun,&Yu, Liangmin.(2017).Lectin functionalized ZnO nanoarrays as a 3D nano-biointerface for bacterial detection.TALANTA,167,600-606. |
| MLA | Zheng, Laibao,et al."Lectin functionalized ZnO nanoarrays as a 3D nano-biointerface for bacterial detection".TALANTA 167(2017):600-606. |
入库方式： OAI收割
来源：海洋研究所
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