Characterization of the IRF2 proteins isolated from the deep-sea mussel Bathymodiolus platifrons and the shallow-water mussel Modiolus modiolus
文献类型：期刊论文
| 作者 | Huang, Baoyu1,2,3 ; Meng, Jie1,2,3; Yang, Mei4,5; Xu, Fei1,3,4; Li, Xinzheng4,5; Li, Li1,2,3; Zhang, Guofan1,3,4
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| 刊名 | DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
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| 出版日期 | 2017-06-01 |
| 卷号 | 71页码:82-87 |
| 关键词 | IRF2 Deep-sea mussel ISRE Innate immunity |
| 英文摘要 | Interferon regulatory factors (IRFs) are transcription factors that play important roles in immune defense, stress response, hematopoietic differentiation, and cell apoptosis. IRFs of invertebrate organisms and their functions remain largely unexplored. In the present study, for the first time new IRFs (BpIRF2 and MmIRF2) were identified in the deep-sea mussel Bathymodiolus platifrons and the shallow-water mussel Modiolus modiolus. The open reading frame of BpIRF2 and MmIRF2 encoded putative proteins of 354 and 348 amino acids, respectively. Comparison and phylogenetic analysis revealed that both IRF2 proteins were new identified invertebrate IRF molecular. As transcriptional factors, both BpIRF2 and MmIRF2 could activate the interferon-stimulated response element-containing promoter and BpIRF2 could interact with itself. Moreover, both BpIRF2 and MmIRF2 were localized to the cytoplasm and nucleus. Collectively, these results demonstrated that IRF2 proteins might be crucial in the innate immunity of deep-sea and shallow-water mussels. (C) 2017 Published by Elsevier Ltd. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000397834800009 |
| 版本 | 出版稿 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/136726]  |
| 专题 | 海洋研究所_海洋生物技术研发中心 海洋研究所_实验海洋生物学重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Fisheries & Aquaculture, Qingdao, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, Natl & Local Joint Engn Lab Ecol Mariculture, Qingdao, Peoples R China 4.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao, Peoples R China 5.Chinese Acad Sci, Dept Marine Organism Taxon & Phylogeny, Qingdao, Peoples R China |
| 推荐引用方式 GB/T 7714 | Huang, Baoyu,Meng, Jie,Yang, Mei,et al. Characterization of the IRF2 proteins isolated from the deep-sea mussel Bathymodiolus platifrons and the shallow-water mussel Modiolus modiolus[J]. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY,2017,71:82-87. |
| APA | Huang, Baoyu.,Meng, Jie.,Yang, Mei.,Xu, Fei.,Li, Xinzheng.,...&Zhang, Guofan.(2017).Characterization of the IRF2 proteins isolated from the deep-sea mussel Bathymodiolus platifrons and the shallow-water mussel Modiolus modiolus.DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY,71,82-87. |
| MLA | Huang, Baoyu,et al."Characterization of the IRF2 proteins isolated from the deep-sea mussel Bathymodiolus platifrons and the shallow-water mussel Modiolus modiolus".DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 71(2017):82-87. |
入库方式： OAI收割
来源：海洋研究所
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