Screening and Structural Characterization of alpha-Glucosidase Inhibitors from Hawthorn Leaf Flavonoids Extract by Ultrafiltration LC-DAD-MSn and SORI-CID FTICR MS
文献类型：期刊论文
| 作者 | Li HL ; Song FR ; Xing JP ; Tsao R ; Liu ZQ ; Liu SY |
| 刊名 | journal of the american society for mass spectrometry
 |
| 出版日期 | 2009 |
| 卷号 | 20期号:8页码:1496-1503 |
| 关键词 | TANDEM MASS-SPECTROMETRY COMBINATORIAL LIBRARIES DIABETES-MELLITUS AFFINITY CONSTITUENTS LIGANDS |
| ISSN号 | 1044-0305 |
| 通讯作者 | liu zq |
| 中文摘要 | in vitro a-glucosidase inhibition assays and ultrafiltration liquid chromatography with photodiode array detection coupled to electrospray ionization tandem mass spectrometry (ultrafiltration lc-dad-esi-msn) were combined to screen a-glucosidase inhibitors from hawthorn leaf flavonoids extract (hlfe). as a result, four compounds were identified as alpha-glucosidase inhibitors in the hlfe, and their structures were confirmed to be quercetin-3-o-rha-(1-4)-glc-rha and c-glycosylflavones (vitexin-2 ''-o-glucoside, vitexin-2 ''-o-rhamnoside and vitexin) by high-resolution sustained off resonance irradiation collision-induced dissociation (sori-cid) data obtained by fourier transform ion cyclotron resonance mass spectrometry (fticr ms). |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000268739900013 |
| 公开日期 | 2010-05-04 |
| 源URL | [http://202.98.16.49/handle/322003/11475]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Li HL,Song FR,Xing JP,et al. Screening and Structural Characterization of alpha-Glucosidase Inhibitors from Hawthorn Leaf Flavonoids Extract by Ultrafiltration LC-DAD-MSn and SORI-CID FTICR MS[J]. journal of the american society for mass spectrometry,2009,20(8):1496-1503. |
| APA | Li HL,Song FR,Xing JP,Tsao R,Liu ZQ,&Liu SY.(2009).Screening and Structural Characterization of alpha-Glucosidase Inhibitors from Hawthorn Leaf Flavonoids Extract by Ultrafiltration LC-DAD-MSn and SORI-CID FTICR MS.journal of the american society for mass spectrometry,20(8),1496-1503. |
| MLA | Li HL,et al."Screening and Structural Characterization of alpha-Glucosidase Inhibitors from Hawthorn Leaf Flavonoids Extract by Ultrafiltration LC-DAD-MSn and SORI-CID FTICR MS".journal of the american society for mass spectrometry 20.8(2009):1496-1503. |
入库方式： OAI收割
来源：长春应用化学研究所
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