Spirostanol saponins from Ypsilandra parviflora induce platelet aggregation
文献类型：期刊论文
| 作者 | Lu, Ting-Xiang1,3; Shu, Tong1,2; Qin, Xu-Jie1 ; Ni, Wei1; Ji, Yun-Heng4; Chen, Qi-Run1,5; Khan, Afsar6; Zhao, Qing5; Liu, Hai-Yang1
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| 刊名 | STEROIDS
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| 出版日期 | 2017-07-01 |
| 卷号 | 123页码:55-60 |
| 关键词 | Ypsilandra parviflora Liliaceae Spirostanol saponins Ypsiparosides A-G Induced platelet aggregation activity |
| 英文摘要 | Phytochemical investigation on the whole plants of Ypsilandra parviflora led to the isolation of seven new spirostanol saponins, named ypsiparosides A-G, together with 14 known saponins. Their structures were unambiguously established based on extensive spectroscopic evidence and chemical methods. The induced rabbit platelet aggregation activities of the isolates were tested. Compounds 4, 15, and 17 showed maximal platelet aggregation rates ranging from 43 to 55% at a concentration of 300 mu g/mL. Further experiments exhibited that compounds 4, 15, and 17 possessed EC50 values of 642.9, 95.3, and 300.8 mu g/mL, respectively. |
| 类目[WOS] | Biochemistry & Molecular Biology ; Endocrinology & Metabolism |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Endocrinology & Metabolism |
| 关键词[WOS] | STEROIDAL SAPONINS ; PARIS-POLYPHYLLA ; BLOOD-PLATELETS ; GLYCOSIDES ; THIBETICA ; YUNNANENSIS ; RHIZOMES |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000403131400008 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/51359]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Qiannan Med Coll Nationalities, Duyun 558000, Peoples R China 4.Chinese Acad Sci, Kunming Inst Bot, Key Lab Plant Biodivers & Biogeog East Asia, Kunming 650201, Peoples R China 5.Yunnan Univ TCM, Coll Tradit Chinese Med, Kunming 650500, Peoples R China 6.COMSATS Inst Informat Technol, Dept Chem, Abbottabad 22060, Pakistan |
| 推荐引用方式 GB/T 7714 | Lu, Ting-Xiang,Shu, Tong,Qin, Xu-Jie,et al. Spirostanol saponins from Ypsilandra parviflora induce platelet aggregation[J]. STEROIDS,2017,123:55-60. |
| APA | Lu, Ting-Xiang.,Shu, Tong.,Qin, Xu-Jie.,Ni, Wei.,Ji, Yun-Heng.,...&Liu, Hai-Yang.(2017).Spirostanol saponins from Ypsilandra parviflora induce platelet aggregation.STEROIDS,123,55-60. |
| MLA | Lu, Ting-Xiang,et al."Spirostanol saponins from Ypsilandra parviflora induce platelet aggregation".STEROIDS 123(2017):55-60. |
入库方式： OAI收割
来源：昆明植物研究所
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