Identification of residues important for the activity of aldehyde-deformylating oxygenase through investigation into the structure-activity relationship
文献类型：期刊论文
| 作者 | Wang, Qing1,2; Bao, Luyao1,2; Jia, Chenjun2,3; Li, Mei3; Li, Jian-Jun1,4; Lu, Xuefeng1 |
| 刊名 | BMC BIOTECHNOLOGY
 |
| 出版日期 | 2017-03-16 |
| 卷号 | 17 |
| 关键词 | Aldehyde-deformylating oxygenase Site-directed mutagenesis Structure-activity relationship Fatty alk(a/e) ne Synechococcus elongatus PCC7942 Synechocystis sp PCC6803 |
| 英文摘要 | Background: Aldehyde-deformylating oxygenase (ADO) is a key enzyme involved in the biosynthetic pathway of fatty alk(a/e)nes in cyanobacteria. However, cADO (cyanobacterial ADO) showed extreme low activity with the k(cat) value below 1 min(-1), which would limit its application in biofuel production. To identify the activity related key residues of cADO is urgently required. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Biotechnology & Applied Microbiology |
| 研究领域[WOS] | Biotechnology & Applied Microbiology |
| 关键词[WOS] | CYANOBACTERIAL ALDEHYDE ; FATTY ALDEHYDES ; DECARBONYLASE ; CONVERSION ; ALKANES ; INSIGHTS ; ENZYMES ; FORMATE |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000396668000001 |
| 源URL | [http://ir.qibebt.ac.cn/handle/337004/9351]  |
| 专题 | 青岛生物能源与过程研究所_微生物代谢工程团队 |
| 作者单位 | 1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Key Lab Biofuels, Shandong Prov Key Lab Energy Genet, Qingdao 266101, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, Beijing 100101, Peoples R China 4.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Qing,Bao, Luyao,Jia, Chenjun,et al. Identification of residues important for the activity of aldehyde-deformylating oxygenase through investigation into the structure-activity relationship[J]. BMC BIOTECHNOLOGY,2017,17. |
| APA | Wang, Qing,Bao, Luyao,Jia, Chenjun,Li, Mei,Li, Jian-Jun,&Lu, Xuefeng.(2017).Identification of residues important for the activity of aldehyde-deformylating oxygenase through investigation into the structure-activity relationship.BMC BIOTECHNOLOGY,17. |
| MLA | Wang, Qing,et al."Identification of residues important for the activity of aldehyde-deformylating oxygenase through investigation into the structure-activity relationship".BMC BIOTECHNOLOGY 17(2017). |
入库方式： OAI收割
来源：青岛生物能源与过程研究所
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