Sensitive detection of cysteine based on fluorescent silver clusters
文献类型：期刊论文
| 作者 | Shang L ; Dong SJ |
| 刊名 | biosensors & bioelectronics
 |
| 出版日期 | 2009 |
| 卷号 | 24期号:6页码:1569-1573 |
| 关键词 | COLLOIDAL SILVER GOLD NANOPARTICLES AG NANOCLUSTERS QUANTUM DOTS SELECTIVE DETECTION SURFACE-CHEMISTRY OPTICAL SENSORS METAL-CLUSTERS BIOSENSORS CHEMISORPTION |
| ISSN号 | 0956-5663 |
| 通讯作者 | dong sj |
| 中文摘要 | in this work,we report the application of novel, water-soluble fluorescent ag clusters in fluorescent sensors for detecting cysteine, an important biological analyte. the fluorescence of poly(methacrylic acid) (pmaa)templated ag clusters was found to be quenched effectively by cysteine, but not when the other alpha-amino acids were present. by virtue of the specific response, a new, simple, and sensitive fluorescent method for detecting cysteine has been developed based on ag clusters. the present assay allows for the selective determination of cysteine in the range of 2.5 x 10(-8) to 6.0 x 10(-6) m with a detection limit of 20 nm at a signal-to-noise ratio of 3. based on the absorption and fluorescence studies, we suggested that cysteine quenched the emission by the thiol-adsorption-accelerated oxidation of the emissive ag clusters. the present study shows a promising step toward the application of silver clusters, a new class of attractive fluorescence probes. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000263778000006 |
| 公开日期 | 2010-05-27 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/11923]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Shang L,Dong SJ. Sensitive detection of cysteine based on fluorescent silver clusters[J]. biosensors & bioelectronics,2009,24(6):1569-1573. |
| APA | Shang L,&Dong SJ.(2009).Sensitive detection of cysteine based on fluorescent silver clusters.biosensors & bioelectronics,24(6),1569-1573. |
| MLA | Shang L,et al."Sensitive detection of cysteine based on fluorescent silver clusters".biosensors & bioelectronics 24.6(2009):1569-1573. |
入库方式： OAI收割
来源：长春应用化学研究所
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