Lewis-Base-Mediated Diastereoselective Silylations of Alcohols: Synthesis of Silicon-Stereogenic Dialkoxysilanes Controlled by Chiral Aryl BINMOLs
文献类型:期刊论文
作者 | Bo XF(柏惺峰)1,2,3; Zou, Jin-Feng1; Chen, Mu-Yi1; Xu, Zheng1; Li, Li1; Cui, Yu-Ming1; Zheng, Zhan-Jiang1; Xu LW(徐利文)1,2,3 |
刊名 | Chemistry - An Asian Journal |
出版日期 | 2017 |
卷号 | 12期号:14页码:1730-1735 |
ISSN号 | 1861-4728 |
关键词 | alcohols chiral silanes diastereoselectivity organocatalysis organosilicon compounds |
通讯作者 | Li, Li ; 徐利文 |
英文摘要 | In the past years, stereoselective functionalizations of hydroxyl groups of alcohol substrates with chlorosilanes leading to silyl ether formation have evolved from a functional-group protection to an enantioselective synthetic strategy. This work comprises a controlled desymmetrization of dichlorosilanes by using a family of structurally specific chiral diols, chiral 1,1-binaphthalene-2--arylmethanol-2-ol (Ar-BINMOL). This process led to the facile construction of silicon-stereogenic organosilicon compounds with high yields and good diastereoselectivities. In addition, the diasteroselective silylation of chiral diols might not only be of interest for the development of highly stereoselective nucleophilic silylation, but also shed light on the construction of novel chiral phosphine ligands bearing a silicon-stereogenic center. |
学科主题 | 物理化学与绿色催化 |
资助信息 | the National Natural Science Foundation of China (No. 21472031;21503060);Zhejiang Provincial Natural Science Foundation of China (LR14B030001;LY16E030009;LY17E030003) |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000405719100011 |
源URL | [http://210.77.64.217/handle/362003/22190] |
专题 | 兰州化学物理研究所_苏州研究院 兰州化学物理研究所_OSSO国家重点实验室 |
作者单位 | 1.Hangzhou Normal Univ, Key Lab Organosilicon Chem & Mat Technol, Minist Educ, Hangzhou 311121, Zhejiang, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Suzhou Res Inst, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China |
推荐引用方式 GB/T 7714 | Bo XF,Zou, Jin-Feng,Chen, Mu-Yi,et al. Lewis-Base-Mediated Diastereoselective Silylations of Alcohols: Synthesis of Silicon-Stereogenic Dialkoxysilanes Controlled by Chiral Aryl BINMOLs[J]. Chemistry - An Asian Journal,2017,12(14):1730-1735. |
APA | Bo XF.,Zou, Jin-Feng.,Chen, Mu-Yi.,Xu, Zheng.,Li, Li.,...&Xu LW.(2017).Lewis-Base-Mediated Diastereoselective Silylations of Alcohols: Synthesis of Silicon-Stereogenic Dialkoxysilanes Controlled by Chiral Aryl BINMOLs.Chemistry - An Asian Journal,12(14),1730-1735. |
MLA | Bo XF,et al."Lewis-Base-Mediated Diastereoselective Silylations of Alcohols: Synthesis of Silicon-Stereogenic Dialkoxysilanes Controlled by Chiral Aryl BINMOLs".Chemistry - An Asian Journal 12.14(2017):1730-1735. |
入库方式: OAI收割
来源:兰州化学物理研究所
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