Direct toxicity assessment of toxic chemicals with electrochemical method
文献类型：期刊论文
| 作者 | Liu C ; Sun T ; Xu XL ; Dong SJ |
| 刊名 | analytica chimica acta
 |
| 出版日期 | 2009 |
| 卷号 | 641期号:1-2页码:59-63 |
| 关键词 | BIOCHEMICAL OXYGEN-DEMAND SACCHAROMYCES-CEREVISIAE LUMINESCENT BACTERIA FERRICYANIDE BIOSENSOR SENSOR BOD MICROORGANISMS SENSITIVITY WASTEWATERS |
| ISSN号 | 0003-2670 |
| 通讯作者 | sun t |
| 中文摘要 | electrochemical measurement of respiratory chain activity is a rapid and reliable screening for the toxicity on microorganisms. here, we investigated in-vitro effects of toxin on escherichia coli (e. coli) that was taken as a model microorganism incubated with ferricyanide. the current signal of ferrocyanide effectively amplified by ultramicroelectrode array (umea), which was proven to be directly related to the toxicity. accordingly, a direct toxicity assessment (dta) based on chronoamperometry was proposed to detect the effect of toxic chemicals on microorganisms. the electrochemical responses to 3,5-dichlorophenol (dcp) under the incubation times revealed that the toxicity reached a stable level at 60 min, and its 50% inhibiting concentration (ic50) was estimated to be 8.0 mg l-1. at 60 min incubation, the ic50 values for kcn and as2o3 in water samples were 4.9 mg l-1 and 18.3 mg l-1, respectively. but the heavy metal ions, such as cu2+ pb2+ and ni2+, showed no obvious toxicity on e. coli. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2010-05-27 ; 2011-06-09 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/12163]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Liu C,Sun T,Xu XL,et al. Direct toxicity assessment of toxic chemicals with electrochemical method[J]. analytica chimica acta,2009,641(1-2):59-63. |
| APA | Liu C,Sun T,Xu XL,&Dong SJ.(2009).Direct toxicity assessment of toxic chemicals with electrochemical method.analytica chimica acta,641(1-2),59-63. |
| MLA | Liu C,et al."Direct toxicity assessment of toxic chemicals with electrochemical method".analytica chimica acta 641.1-2(2009):59-63. |
入库方式： OAI收割
来源：长春应用化学研究所
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