Uncovering the rules for protein-protein interactions from yeast genomic data
文献类型:期刊论文
作者 | Wang J ; Li CH ; Wang E ; Wang XD |
刊名 | proceedings of the national academy of sciences of the united states of america
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出版日期 | 2009 |
卷号 | 106期号:10页码:3752-3757 |
关键词 | MITOCHONDRIAL RIBOSOMAL-PROTEINS SACCHAROMYCES-CEREVISIAE BAYESIAN NETWORKS DATA INTEGRATION EXPRESSION DATA IDENTIFICATION GENERATION ALGORITHM SEQUENCES COMPLEX |
ISSN号 | 0027-8424 |
通讯作者 | wang e |
中文摘要 | identifying protein-protein interactions is crucial for understanding cellular functions. genomic data provides opportunities and challenges in identifying these interactions. we uncover the rules for predicting protein-protein interactions using a frequent pattern tree (fpt) approach modified to generate a minimum set of rules (mfpt), with rule attributes constructed from the interaction features of the yeast genomic data. the mfpt prediction accuracy is benchmarked against other commonly used methods such as bayesian networks and logistic regressions under various statistical measures. our study indicates that mfpt outranks other methods in predicting the protein-protein interactions for the database used. we predict a new protein-protein interaction complex whose biological function is related to premrna splicing and new protein-protein interactions within existing complexes based on the rules generated. |
收录类别 | CHEM. SOC. REV., ACC.CHEM. RES, PNAS |
语种 | 英语 |
WOS记录号 | WOS:000264036900022 |
公开日期 | 2010-05-27 |
源URL | [http://202.98.16.49/handle/322003/12185] ![]() |
专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
推荐引用方式 GB/T 7714 | Wang J,Li CH,Wang E,et al. Uncovering the rules for protein-protein interactions from yeast genomic data[J]. proceedings of the national academy of sciences of the united states of america,2009,106(10):3752-3757. |
APA | Wang J,Li CH,Wang E,&Wang XD.(2009).Uncovering the rules for protein-protein interactions from yeast genomic data.proceedings of the national academy of sciences of the united states of america,106(10),3752-3757. |
MLA | Wang J,et al."Uncovering the rules for protein-protein interactions from yeast genomic data".proceedings of the national academy of sciences of the united states of america 106.10(2009):3752-3757. |
入库方式: OAI收割
来源:长春应用化学研究所
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