中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Uncovering the rules for protein-protein interactions from yeast genomic data

文献类型:期刊论文

作者Wang J ; Li CH ; Wang E ; Wang XD
刊名proceedings of the national academy of sciences of the united states of america
出版日期2009
卷号106期号:10页码:3752-3757
关键词MITOCHONDRIAL RIBOSOMAL-PROTEINS SACCHAROMYCES-CEREVISIAE BAYESIAN NETWORKS DATA INTEGRATION EXPRESSION DATA IDENTIFICATION GENERATION ALGORITHM SEQUENCES COMPLEX
ISSN号0027-8424
通讯作者wang e
中文摘要identifying protein-protein interactions is crucial for understanding cellular functions. genomic data provides opportunities and challenges in identifying these interactions. we uncover the rules for predicting protein-protein interactions using a frequent pattern tree (fpt) approach modified to generate a minimum set of rules (mfpt), with rule attributes constructed from the interaction features of the yeast genomic data. the mfpt prediction accuracy is benchmarked against other commonly used methods such as bayesian networks and logistic regressions under various statistical measures. our study indicates that mfpt outranks other methods in predicting the protein-protein interactions for the database used. we predict a new protein-protein interaction complex whose biological function is related to premrna splicing and new protein-protein interactions within existing complexes based on the rules generated.
收录类别CHEM. SOC. REV., ACC.CHEM. RES, PNAS
语种英语
WOS记录号WOS:000264036900022
公开日期2010-05-27
源URL[http://202.98.16.49/handle/322003/12185]  
专题长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
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GB/T 7714
Wang J,Li CH,Wang E,et al. Uncovering the rules for protein-protein interactions from yeast genomic data[J]. proceedings of the national academy of sciences of the united states of america,2009,106(10):3752-3757.
APA Wang J,Li CH,Wang E,&Wang XD.(2009).Uncovering the rules for protein-protein interactions from yeast genomic data.proceedings of the national academy of sciences of the united states of america,106(10),3752-3757.
MLA Wang J,et al."Uncovering the rules for protein-protein interactions from yeast genomic data".proceedings of the national academy of sciences of the united states of america 106.10(2009):3752-3757.

入库方式: OAI收割

来源:长春应用化学研究所

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