中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Monodisperse mesoporous superparamagnetic single-crystal magnetite nanoparticles for drug delivery

文献类型:期刊论文

作者Guo SJ ; Li D ; Zhang LM ; Li J ; Wang EK
刊名biomaterials
出版日期2009
卷号30期号:10页码:1881-1889
关键词IRON-OXIDE NANOPARTICLES ONE-POT SYNTHESIS IN-VIVO NANOCRYSTALS THERAPY NANOSTRUCTURES PARTICLES VESICLES CANCER PHASE
ISSN号0142-9612
通讯作者wang ek
中文摘要in this contribution, we report a facile, gram-scale, low-cost route to prepare monodisperse superparamagnetic single-crystal magnetite nps with mesoporous structure (mssmn) via a very simple solvothermal method. the formation mechanism of mssmn is also discussed and we think that ostwald ripening probably plays an important role in this synthesis process. it is also interestingly found that the size and morphology of mesoporous fe3o4 nps can be easily controlled by changing the amount of naoh and 1,2-ethylenediamine (eth). most importantly, the mssmn can be used as an effective drug delivery carrier. a typical anticancer drug, doxorubicin (dox), is used for drug loading, and the release behaviors of dox in two different ph solutions are studied. the results indicate that the mssmn has a high drug loading capacity and favorable release property for dox; thus, it is very promising for the application in drug delivery.
收录类别SCI
语种英语
WOS记录号WOS:000264145800003
公开日期2010-05-27
源URL[http://202.98.16.49/handle/322003/12187]  
专题长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
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GB/T 7714
Guo SJ,Li D,Zhang LM,et al. Monodisperse mesoporous superparamagnetic single-crystal magnetite nanoparticles for drug delivery[J]. biomaterials,2009,30(10):1881-1889.
APA Guo SJ,Li D,Zhang LM,Li J,&Wang EK.(2009).Monodisperse mesoporous superparamagnetic single-crystal magnetite nanoparticles for drug delivery.biomaterials,30(10),1881-1889.
MLA Guo SJ,et al."Monodisperse mesoporous superparamagnetic single-crystal magnetite nanoparticles for drug delivery".biomaterials 30.10(2009):1881-1889.

入库方式: OAI收割

来源:长春应用化学研究所

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