One-Step Synthesis of Folic Acid Protected Gold Nanoparticles and Their Receptor-Mediated Intracellular Uptake
文献类型：期刊论文
| 作者 | Li GP ; Li D ; Zhang LX ; Zhai JF ; Wang EK |
| 刊名 | chemistry-a european journal
 |
| 出版日期 | 2009 |
| 卷号 | 15期号:38页码:9868-9873 |
| ISSN号 | 0947-6539 |
| 关键词 | SURFACE MODIFICATION CELLULAR UPTAKE CELLS NANORODS DELIVERY THERAPY CITRATE AGENTS FUNGUS SIZE |
| 通讯作者 | wang ek |
| 中文摘要 | we report here a facile method to obtain folic acid (fa)-protected gold nanoparticles (au nps) by heating an aqueous solution of haucl4/fa in which fa acts as both the reducing and stabilizing agent. the successful formation of fa-protected au nps is demonstrated by uv/vis spectroscopy, transmission electron microscopy (tem), selected-area electron diffraction (saed), x-ray photoelectron spectroscopy (xps), and fourier transform infrared spectroscopy (ftir). ne intracellular uptake of these nanoparticles is facilitated by hela cells overexpressing the folate reporter, which itself is significantly inhibited by free fa in a competitive assay as quantified by inductively coupled plasma mass spectroscopy (icp-ms). this simple one-step approach affords a new perspective for creating functional nanomaterials, and the resulting biocompatible, functional au nps may find some prospective applications in various biomedical fields. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000270435600030 |
| 公开日期 | 2010-05-27 |
| 源URL | [http://202.98.16.49/handle/322003/12195]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Li GP,Li D,Zhang LX,et al. One-Step Synthesis of Folic Acid Protected Gold Nanoparticles and Their Receptor-Mediated Intracellular Uptake[J]. chemistry-a european journal,2009,15(38):9868-9873. |
| APA | Li GP,Li D,Zhang LX,Zhai JF,&Wang EK.(2009).One-Step Synthesis of Folic Acid Protected Gold Nanoparticles and Their Receptor-Mediated Intracellular Uptake.chemistry-a european journal,15(38),9868-9873. |
| MLA | Li GP,et al."One-Step Synthesis of Folic Acid Protected Gold Nanoparticles and Their Receptor-Mediated Intracellular Uptake".chemistry-a european journal 15.38(2009):9868-9873. |
入库方式： OAI收割
来源：长春应用化学研究所
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