Colorimetric recognition of the coralyne-poly(dA) interaction using unmodified gold nanoparticle probes, and further detection of coralyne based upon this recognition system
文献类型：期刊论文
| 作者 | Lv ZZ ; Wei H ; Li BL ; Wang EK |
| 刊名 | analyst
 |
| 出版日期 | 2009 |
| 卷号 | 134期号:8页码:1647-1651 |
| 关键词 | MAMMALIAN TOPOISOMERASE-I NUCLEIC-ACID APTAMERS ADENINE DNA DUPLEX STRUCTURAL SELECTIVITY CONFORMATIONAL SWITCH BINDING LIGANDS INTERCALATION TARGET DISPROPORTIONATION POLYNUCLEOTIDES |
| ISSN号 | 0003-2654 |
| 通讯作者 | wang ek |
| 中文摘要 | among the functional nucleic acids studied, adenine-rich nucleic acids have attracted attention due to their critical roles in many biological processes and self-assembly-based nanomaterials, especially deoxyribonucleic acids (abbreviated as poly(da)). therefore the ligands binding to poly(da) might serve as potential therapeutic agents. coralyne, a kind of planar alkaloid, has been firstly found that it could bind strongly to poly(da). this work herein reports an approach for visual sensing of the coralyne-poly(da) interaction. this method was based on the coralyne inducing poly(da) into the homo-adenine dna duplex and the difference in electrostatic affinity between single-stranded dna and double-stranded dna with gold nanoparticles (gnps). furthermore, we applied the recognition process of the interaction between coralyne and poly(da) into specific coralyne detection with the assistance of certain software (such as photoshop). a linear response from 0 to 728 nm was obtained for coralyne, and a detection limit of 91 nm was achieved. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000268131500020 |
| 公开日期 | 2010-05-27 |
| 源URL | [http://202.98.16.49/handle/322003/12211]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Lv ZZ,Wei H,Li BL,et al. Colorimetric recognition of the coralyne-poly(dA) interaction using unmodified gold nanoparticle probes, and further detection of coralyne based upon this recognition system[J]. analyst,2009,134(8):1647-1651. |
| APA | Lv ZZ,Wei H,Li BL,&Wang EK.(2009).Colorimetric recognition of the coralyne-poly(dA) interaction using unmodified gold nanoparticle probes, and further detection of coralyne based upon this recognition system.analyst,134(8),1647-1651. |
| MLA | Lv ZZ,et al."Colorimetric recognition of the coralyne-poly(dA) interaction using unmodified gold nanoparticle probes, and further detection of coralyne based upon this recognition system".analyst 134.8(2009):1647-1651. |
入库方式： OAI收割
来源：长春应用化学研究所
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