PIFA-Mediated Oxidative Cyclization of 1-Carbamoyl-1-oximylcycloalkanes: Synthesis of Spiro-Fused Pyrazolin-5-one N-Oxides
文献类型：期刊论文
| 作者 | Wang KW ; Fu XL ; Liu JY ; Liang YJ ; Dong DW |
| 刊名 | organic letters
 |
| 出版日期 | 2009 |
| 卷号 | 11期号:4页码:1015-1018 |
| 关键词 | HYPERVALENT IODINE OXIDATION EFFICIENT SYNTHESIS INTRAMOLECULAR CYCLIZATION PHARMACOLOGICAL-PROPERTIES OLEFIN AMIDOHYDROXYLATION ACYLNITRENIUM IONS ALKYNE AMIDATION BOND FORMATION X-RAY DERIVATIVES |
| ISSN号 | 1523-7060 |
| 通讯作者 | dong dw |
| 中文摘要 | convenient and efficient synthesis of spiro-fused pyrazolin-5-one n-oxides starting from readily available 1-carbamoyl-1-oximylcycloalkanes is developed. this general protocol features a novel and facile way for access to the five-membered azaheterocycles by formation of a new n-n single bond. the key cyclization step utilizes the formation of an n-oxonitrenium intermediate, mediated by the hypervalent iodine reagent pifa, and its subsequent intramolecular trapping by the amide moiety under rather mild experimental conditions. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000263299000058 |
| 公开日期 | 2010-05-27 |
| 源URL | [http://202.98.16.49/handle/322003/12543]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Wang KW,Fu XL,Liu JY,et al. PIFA-Mediated Oxidative Cyclization of 1-Carbamoyl-1-oximylcycloalkanes: Synthesis of Spiro-Fused Pyrazolin-5-one N-Oxides[J]. organic letters,2009,11(4):1015-1018. |
| APA | Wang KW,Fu XL,Liu JY,Liang YJ,&Dong DW.(2009).PIFA-Mediated Oxidative Cyclization of 1-Carbamoyl-1-oximylcycloalkanes: Synthesis of Spiro-Fused Pyrazolin-5-one N-Oxides.organic letters,11(4),1015-1018. |
| MLA | Wang KW,et al."PIFA-Mediated Oxidative Cyclization of 1-Carbamoyl-1-oximylcycloalkanes: Synthesis of Spiro-Fused Pyrazolin-5-one N-Oxides".organic letters 11.4(2009):1015-1018. |
入库方式： OAI收割
来源：长春应用化学研究所
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