Fluorescent conjugated polymer-stabilized gold nanoparticles for sensitive and selective detection of cysteine
文献类型：期刊论文
| 作者 | Shang L ; Qin CJ ; Wang T ; Wang M ; Wang LX ; Dong SJ |
| 刊名 | journal of physical chemistry c
 |
| 出版日期 | 2007 |
| 卷号 | 111期号:36页码:13414-13417 |
| 关键词 | TAGGED OLIGONUCLEOTIDE PROBES ENERGY-TRANSFER THIOLS WATER POLYFLUORENES COMPLEXES COLLOIDS SENSORS SYSTEM ASSAY |
| ISSN号 | 1932-7447 |
| 通讯作者 | wang lx |
| 中文摘要 | we report a new fluorescent detection method for cysteine based on one-step prepared fluorescent conjugated polymer-stabilized gold nanoparticles. the as-prepared fluorescent conjugated polymer-stabilized gold nanoparticles fluoresce weakly due to the fluorescence resonance energy transfer between the fluorophore and the gold nanoparticles. upon the addition of cysteine, a thiol-containing amino acid, the fluorescence of the colloidal solution increases significantly, indicating that cysteine can modulate the energy transfer between fluorophore and gold. this phenomenon then allows for sensitive detection of cysteine with a limit of detection (lod) of 25 nm. the linear range of determination of cysteine is from 5 x 10(-8) to 4 x 10(-6) m. none of the other amino acids found in proteins interferes with the determination. moreover, due to the excellent protecting ability of the fluorescent conjugated polymers, the synthesis of metal nanoparticles and modifying with fluorophores can be accomplished within one step, which makes our method much simpler than conventional methods. we also expect that it will be possible to detect other biologically important analytes based on the fluorescent conjugated polymer-stabilized metal nanoparticles. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000249329600019 |
| 公开日期 | 2010-06-18 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/12601]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Shang L,Qin CJ,Wang T,et al. Fluorescent conjugated polymer-stabilized gold nanoparticles for sensitive and selective detection of cysteine[J]. journal of physical chemistry c,2007,111(36):13414-13417. |
| APA | Shang L,Qin CJ,Wang T,Wang M,Wang LX,&Dong SJ.(2007).Fluorescent conjugated polymer-stabilized gold nanoparticles for sensitive and selective detection of cysteine.journal of physical chemistry c,111(36),13414-13417. |
| MLA | Shang L,et al."Fluorescent conjugated polymer-stabilized gold nanoparticles for sensitive and selective detection of cysteine".journal of physical chemistry c 111.36(2007):13414-13417. |
入库方式： OAI收割
来源：长春应用化学研究所
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