Interactions of Rare Earth-Amino Acid Complexes with Nucleic Acids
文献类型：期刊论文
| 作者 | Geng J ; Yu HJ ; Zhang HY ; Xu HX ; Qu XG |
| 刊名 | progress in chemistry
 |
| 出版日期 | 2009 |
| 卷号 | 21期号:5页码:866-872 |
| 关键词 | PHYSIOLOGICAL PH CONDITIONS RNA-PROCESSING ENZYME ENERGY-TRANSFER DNA STRUCTURES CUBANE-LIKE COORDINATION CLUSTER DESIGN RECOGNITION INHIBITION |
| ISSN号 | 1005-281x |
| 通讯作者 | geng j |
| 中文摘要 | a number of metal-based anticancer drugs are designed to target nucleic acids. therefore, the elucidation of their interactions with nucleic acids is important for rational design of new anticancer agents with high selectivity and low toxicity, which has been received much attention in this field. lanthanide complexes have the potential to be therapeutic agents due to their unique magnetic, optical, electronic, and coordinate characteristics. however, lanthanide ions are easy to hydrolysis under physiological ph, which makes it difficult to study rare earth complexes nucleic acids selectivity. recent studies have shown that natural amino acids can form stable complexes with rare earth ions under near physiological condition and the complexes have high solubility. this review summarizes the current progress in rare earth-amino acid complexes binding to nuclelic acids and their selectivity. |
| 收录类别 | SCI |
| 语种 | 中文 |
| WOS记录号 | WOS:000266016000008 |
| 公开日期 | 2010-06-18 |
| 源URL | [http://202.98.16.49/handle/322003/12721]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Geng J,Yu HJ,Zhang HY,et al. Interactions of Rare Earth-Amino Acid Complexes with Nucleic Acids[J]. progress in chemistry,2009,21(5):866-872. |
| APA | Geng J,Yu HJ,Zhang HY,Xu HX,&Qu XG.(2009).Interactions of Rare Earth-Amino Acid Complexes with Nucleic Acids.progress in chemistry,21(5),866-872. |
| MLA | Geng J,et al."Interactions of Rare Earth-Amino Acid Complexes with Nucleic Acids".progress in chemistry 21.5(2009):866-872. |
入库方式： OAI收割
来源：长春应用化学研究所
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