Studies on the Interaction between Single-strand Oligonucleotide and Ginsenosides by Electrospray Ionization Mass Spectrometry
文献类型:期刊论文
作者 | Song FR ; Yan CY ; Liu N ; Liu ZQ ; Liu SY |
刊名 | acta chimica sinica |
出版日期 | 2009 |
卷号 | 67期号:10页码:1103-1108 |
ISSN号 | 0567-7351 |
关键词 | NONCOVALENT COMPLEXES DNA BINDING OLIGODEOXYNUCLEOTIDE GINSENG GC |
通讯作者 | song fr |
中文摘要 | oligonucleotide from sars virus was selected as a target molecule in the paper. the noncovalent complexes of ginsenosides with the target molecule were investigated by electrospray ionization mass spectrometry. the effects of experimental conditions were examined firstly on the formation of noncovalent complexes. based on the optimized experimental conditions, the interaction of different ginsenosides with the target molecule was researched, finding that the interaction orders are relative with the structure of aglycons, the length and terminal sugar types of saccharide chains in the ginsenosides. there are certain rules for the interaction between the ginsenosides and dna target molecule. for different type ginsenosides, the interaction intensity takes the orders 20-s-protopanaxatriol > 20-s-protopanaxadiol, and panaxatriol ginsenosides > panaxadiol ginsenosides. for the ginsenosides with the same type aglycone, tri-saccharide chain > di-saccharide chain > tetra-saccharide chain and single-saccharide chain > panaxatriol. for the ginsenosides with the same tetra-saccharide chain, the ginsenosides with smaller molecule masses > the ginsenosides with larger molecule masses. |
收录类别 | SCI |
语种 | 中文 |
WOS记录号 | WOS:000266942300012 |
公开日期 | 2010-06-18 |
源URL | [http://202.98.16.49/handle/322003/12827] |
专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
推荐引用方式 GB/T 7714 | Song FR,Yan CY,Liu N,et al. Studies on the Interaction between Single-strand Oligonucleotide and Ginsenosides by Electrospray Ionization Mass Spectrometry[J]. acta chimica sinica,2009,67(10):1103-1108. |
APA | Song FR,Yan CY,Liu N,Liu ZQ,&Liu SY.(2009).Studies on the Interaction between Single-strand Oligonucleotide and Ginsenosides by Electrospray Ionization Mass Spectrometry.acta chimica sinica,67(10),1103-1108. |
MLA | Song FR,et al."Studies on the Interaction between Single-strand Oligonucleotide and Ginsenosides by Electrospray Ionization Mass Spectrometry".acta chimica sinica 67.10(2009):1103-1108. |
入库方式: OAI收割
来源:长春应用化学研究所
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