Simultaneous detoxification and preparative separation of chlorogenic acid from Eupatorium adenophorum by combined column chromatography
文献类型：期刊论文
| 作者 | Liu, Boyan1,2; Dong, Beitao1,2; Yuan, Xiaofan1 ; Guo, Yuanheng1,2; Zhang, Lijun1,2; Zhao, Bing1
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| 刊名 | SEPARATION SCIENCE AND TECHNOLOGY
 |
| 出版日期 | 2017 |
| 卷号 | 52期号:6页码:1114-1121 |
| 关键词 | Chlorogenic acid Eupatorium adenophorum Spreng macroporous resin 9-oxo-10 11-dehydroageraphorone polyamide resin |
| ISSN号 | 0149-6395 |
| 英文摘要 | An efficient method for simultaneous detoxification and preparative separation of chlorogenic acid from Eupatorium adenophorum was developed. The entire procedure consisted of two separation steps. The first step was enrichment of chlorogenic acid from the crude extract by NKA-II macroporous resin. The purity of chlorogenic acid increased from 5.3% to 20.9% with a recovery of 88.7%. Subsequently, polyamide resin was used to achieve a higher purity. After the polyamide resin treatment, the main toxin 9-oxo-10,11-dehydroageraphorone was removed and the purity of chlorogenic acid reached 86.5% with a recovery of 84.8%. It provided a new way for the utilization of E. adenophorum. |
| WOS标题词 | Science & Technology ; Physical Sciences ; Technology |
| 类目[WOS] | Chemistry, Multidisciplinary ; Engineering, Chemical |
| 研究领域[WOS] | Chemistry ; Engineering |
| 关键词[WOS] | PERFORMANCE LIQUID-CHROMATOGRAPHY ; COUNTER-CURRENT CHROMATOGRAPHY ; POLYAMIDE RESIN ; MACROPOROUS RESINS ; AGERATINA-ADENOPHORA ; CAFFEIC ACID ; NATURAL-PRODUCTS ; PURIFICATION ; ADSORPTION ; EXTRACT |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000399643200014 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/22477]  |
| 专题 | 过程工程研究所_生化工程国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Proc Engn, Div Biorefinery Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Boyan,Dong, Beitao,Yuan, Xiaofan,et al. Simultaneous detoxification and preparative separation of chlorogenic acid from Eupatorium adenophorum by combined column chromatography[J]. SEPARATION SCIENCE AND TECHNOLOGY,2017,52(6):1114-1121. |
| APA | Liu, Boyan,Dong, Beitao,Yuan, Xiaofan,Guo, Yuanheng,Zhang, Lijun,&Zhao, Bing.(2017).Simultaneous detoxification and preparative separation of chlorogenic acid from Eupatorium adenophorum by combined column chromatography.SEPARATION SCIENCE AND TECHNOLOGY,52(6),1114-1121. |
| MLA | Liu, Boyan,et al."Simultaneous detoxification and preparative separation of chlorogenic acid from Eupatorium adenophorum by combined column chromatography".SEPARATION SCIENCE AND TECHNOLOGY 52.6(2017):1114-1121. |
入库方式： OAI收割
来源：过程工程研究所
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