Physical and spectral characterization of the human cyclin A gene and its interactions with anthracycline anticancer drugs
文献类型:期刊论文
作者 | Bao HX ; Wang XH ; Yu HJ ; Fu ML ; Qu XG ; Zheng YC ; Ren JS |
刊名 | chemical physics letters
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出版日期 | 2007 |
卷号 | 436期号:1-3页码:252-257 |
关键词 | DEPENDENT KINASE-2 ACID COMPLEX DNA-BINDING CELL-CYCLE EXPRESSION CANCER OVEREXPRESSION TRANSCRIPTION INHIBITION TRANSITION |
ISSN号 | 0009-2614 |
通讯作者 | qu xg |
中文摘要 | over expression of cyclin a in human tumors has been linked to cancer by various experimental lines of evidence. however, physical and spectral characterization of the human cyclin a gene and its interactions with anticancer drugs have not been reported. our gene sequence analysis, singular value decomposition method and melting studies in the presence of antitumor agents, daunomycin, doxorubicin and hoechst 33258 showed that cyclin a gene had both at-rich and gc-rich domains. for a ligand with unknown dna binding specificity, this gene sequence can be used to differentiate its dna binding preference. |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000244946400048 |
公开日期 | 2010-07-13 |
源URL | [http://ir.ciac.jl.cn/handle/322003/14109] ![]() |
专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
推荐引用方式 GB/T 7714 | Bao HX,Wang XH,Yu HJ,et al. Physical and spectral characterization of the human cyclin A gene and its interactions with anthracycline anticancer drugs[J]. chemical physics letters,2007,436(1-3):252-257. |
APA | Bao HX.,Wang XH.,Yu HJ.,Fu ML.,Qu XG.,...&Ren JS.(2007).Physical and spectral characterization of the human cyclin A gene and its interactions with anthracycline anticancer drugs.chemical physics letters,436(1-3),252-257. |
MLA | Bao HX,et al."Physical and spectral characterization of the human cyclin A gene and its interactions with anthracycline anticancer drugs".chemical physics letters 436.1-3(2007):252-257. |
入库方式: OAI收割
来源:长春应用化学研究所
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