Electroactive oligoaniline-containing self-assembled monolayers for tissue engineering applications
文献类型：期刊论文
| 作者 | Guo Y ; Li MY ; Mylonakis A ; Han JJ ; MacDiarmid AG ; Chen XS ; Lelkes PI ; Wei Y |
| 刊名 | biomacromolecules
 |
| 出版日期 | 2007 |
| 卷号 | 8期号:10页码:3025-3034 |
| 关键词 | ELECTRICALLY CONDUCTING POLYMER IN-VITRO PHEOCHROMOCYTOMA CELLS POLYANILINE POLYPYRROLE BIOCOMPATIBILITY BIOMATERIALS ADHESION VIVO DIFFERENTIATION |
| ISSN号 | 1525-7797 |
| 通讯作者 | lelkes pi |
| 中文摘要 | a novel electroactive silsesquioxane precursor, n-(4-aminophenyl)-m-(4'-(3-triethoxysilyl-propyl-ureido) phenyl-1,4-quinonenediimine) (atqd), was successfully synthesized from the emeraldine form of amino-capped aniline trimers via a one-step coupling reaction and subsequent purification by column chromatography. the physicochemical properties of atqd were characterized using mass spectrometry as well as by nuclear magnetic resonance and uv-vis spectroscopy. analysis by cyclic voltammetry confirmed that the intrinsic electroactivity of atqd was maintained upon protonic acid doping, exhibiting two distinct reversible oxidative states, similar to polyaniline. the aromatic amine terminals of self-assembled monolayers (sams) of atqd on glass substrates were covalently modified with an adhesive oligopeptide, cyclic arg-gly-asp (rgd) (atqd-rgd). the mean height of the monolayer coating on the surfaces was similar to 3 nm, as measured by atomic force microscopy. the biocompatibility of the novel electroactive substrates was evaluated using pc12 pheochromocytoma cells, an established cell line of neural origin. the bioactive, derivatized electroactive scaffold material, atqd-rgd, supported pc12 cell adhesion and proliferation, similar to control tissue-culture-treated polystyrene surfaces. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000250009900008 |
| 公开日期 | 2010-07-13 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/14691]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Guo Y,Li MY,Mylonakis A,et al. Electroactive oligoaniline-containing self-assembled monolayers for tissue engineering applications[J]. biomacromolecules,2007,8(10):3025-3034. |
| APA | Guo Y.,Li MY.,Mylonakis A.,Han JJ.,MacDiarmid AG.,...&Wei Y.(2007).Electroactive oligoaniline-containing self-assembled monolayers for tissue engineering applications.biomacromolecules,8(10),3025-3034. |
| MLA | Guo Y,et al."Electroactive oligoaniline-containing self-assembled monolayers for tissue engineering applications".biomacromolecules 8.10(2007):3025-3034. |
入库方式： OAI收割
来源：长春应用化学研究所
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