Direct electrochemical detection of glucose in human plasma on capillary electrophoresis microchips
文献类型：期刊论文
| 作者 | Du Y ; Yan JL ; Zhou WZ ; Yang XY ; Wang EK |
| 刊名 | electrophoresis
 |
| 出版日期 | 2004 |
| 卷号 | 25期号:21-22页码:3853-3859 |
| 关键词 | PULSED AMPEROMETRIC DETECTION HYDROGEN-PEROXIDE LIQUID-CHROMATOGRAPHY FILM DECOUPLER ELECTRODE FLOW CHEMILUMINESCENCE SYSTEM MICROELECTRODES ANTIBIOTICS |
| ISSN号 | 0173-0835 |
| 通讯作者 | wang ek |
| 中文摘要 | we developed an electrochemical detector on a hybrid chip for the determination of glucose in human plasma. the microchip system described in this paper consists of a poly(dimethylsiloxane) (pdms) layer containing separation and injection channels and an electrode plate. the copper microelectrode is fabricated by selective electroless deposition. the fabrication of the decoupler is performed by platinum electrochemical deposition on the metal film formed by electroless deposition. factors influencing the performance, including detection potential, separation field strength, and buffer concentration, were studied. the electrodes exhibited good stability and durability in the analytical procedures. under optimized detection conditions, glucose responded linearly from 10 mum to 1 mm. finally, glucose in human plasma from three healthy individuals and two diabetics was successfully determined, giving a good prospect for a new clinical diagnostic instrument. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000225679000038 |
| 公开日期 | 2010-08-17 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/14803]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Du Y,Yan JL,Zhou WZ,et al. Direct electrochemical detection of glucose in human plasma on capillary electrophoresis microchips[J]. electrophoresis,2004,25(21-22):3853-3859. |
| APA | Du Y,Yan JL,Zhou WZ,Yang XY,&Wang EK.(2004).Direct electrochemical detection of glucose in human plasma on capillary electrophoresis microchips.electrophoresis,25(21-22),3853-3859. |
| MLA | Du Y,et al."Direct electrochemical detection of glucose in human plasma on capillary electrophoresis microchips".electrophoresis 25.21-22(2004):3853-3859. |
入库方式： OAI收割
来源：长春应用化学研究所
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